Gene detail

D1N57_RS05745

Histidine kinase, Classic

Clostridioides difficile · GCF_007001195

ClassHKTypeClassicLength900 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_007001195#D1N57_RS05745Stable P2CS identifier used across views.
GenomeGCF_007001195Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0405720Run 6 · 95 sequences · id 100% · cov 80%
External referencesWP_021366764.1 · A0A069AHS9 · MIST4 D1N57_RS05745RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

KdpDGAF_3HisKAHATPase_c
Protein length900 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage514 / 900 aa (57.1%)Merged over positioned domains only.
Domain description1 KdpD,1 GAF_3,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa900 aa
KdpD: 22-230 aa (209 aa)1GAF_3: 533-656 aa (124 aa)2HisKA: 676-743 aa (68 aa)3HATPase_c: 787-899 aa (113 aa)4
Domain-by-domain annotation4 items
1 KdpD#1
22-230 aa · 209 aa · 23.2% of protein
Raw tokenKdpD:22:1.56e-133:230:209:210
2 GAF_3#2
533-656 aa · 124 aa · 13.8% of protein
Raw tokenGAF_3:533:0.00000572:656:129:129
3 HisKA#3
676-743 aa · 68 aa · 7.6% of protein
Raw tokenHisKA:676:0.00000000000586:743:68:64
4 HATPase_c#4
787-899 aa · 113 aa · 12.6% of protein
Raw tokenHATPase_c:787:1.97e-30:899:113:109
  • Raw architecture: KdpD:22:1.56e-133:230:209:210#GAF_3:533:0.00000572:656:129:129#HisKA:676:0.00000000000586:743:68:64#HATPase_c:787:1.97e-30:899:113:109
  • Domain description: 1 KdpD,1 GAF_3,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_007001195::NZ_QWVD01000003.1::G00041
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span258890-262324Genomic interval covered by the local TCS group.
Identifiers
Old locus tagD1N57_05745RefSeq proteinWP_021366764.1
Context group IDGCF_007001195::NZ_QWVD01000003.1::G00041
Context members
D1N57_RS05740D1N57_RS05745
Partner locus tags
D1N57_RS05740D1N57_RS05745
Partner old locus tags
D1N57_05740D1N57_05745
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_021366764.1Primary protein accession used for annex mappings.
UniProt accessionA0A069AHS9Primary UniProt accession resolved in the annex database.
UniProt IDA0A069AHS9_CLODIDisplay identifier provided by UniProt.
GO / PubMed5 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagD1N57_RS05745Primary locus identifier stored in the genes table.
Old locus tagD1N57_05745Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QWVD01000003.1Sequence record reported by the local genomic context database.
Genomic interval259 622-262 324 nt2 703 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span258 890-262 324 ntGCF_007001195::NZ_QWVD01000003.1::G00041

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_007001195::NZ_QWVD01000003.1::G00041

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QWVD01000003.1All displayed genes belong to this local TCS context.
Neighborhood span258 890-262 324 nt3 435 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
258 890 nt262 324 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

D1N57_RS05740GCF_007001195#D1N57_RS05740
RROmpR

258 890-259 588 nt · Reverse (-)

Old locus D1N57_05740RefSeq WP_003439430.1
D1N57_RS05745GCF_007001195#D1N57_RS05745
HKClassicCurrent focus

259 622-262 324 nt · Reverse (-)

Old locus D1N57_05745RefSeq WP_021366764.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0405720Run 6 · HK · 95 sequences
Representative sequenceGCF_000448765#QC5_RS09425Use this link to inspect the representative gene detail.
PFAM architectureKdpD + DUF4118 + HisKA + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0405720

Simplified PFAM architecture for HKOC_0405720

PFAM domain coverage: 494 / 900 aa (54.9%)

1 aa900 aa
KdpD: 22-230 aaKdpDDUF4118: 409-514 aaDUF4118HisKA: 676-743 aaHisKAHATPase_c: 788-898 aaHATPase_c
KdpDDUF4118HisKAHATPase_c
  • Simplified architecture: KdpD + DUF4118 + HisKA + HATPase_c
  • Raw architecture: KdpD[22-230] | DUF4118[409-514] | HisKA[676-743] | HATPase_c[788-898]
  • Domain count: 4
  • Matched identifier: HKOC_0405720
  • Positioned domains: KdpD 22-230 ; DUF4118 409-514 ; HisKA 676-743 ; HATPase_c 788-898
Cluster members and taxonomy
Visualization

Representative gene: GCF_000448765#QC5_RS09425

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 95 total members. Page 1 / 2.

GCF_000448765#QC5_RS09425 (representative)
QC5_RS09425 · HK · Classic
RefSeq: WP_021366764.1
UniProt: A0A069AHS9
GCF_000449705#QGM_RS09535
QGM_RS09535 · HK · Classic
RefSeq: WP_021366764.1
UniProt: A0A069AHS9
GCF_000452265#C673_RS09355
C673_RS09355 · HK · Classic
RefSeq: WP_021366764.1
UniProt: A0A069AHS9
GCF_000452285#C674_RS09115
C674_RS09115 · HK · Classic
RefSeq: WP_021366764.1
UniProt: A0A069AHS9
GCF_000452305#C675_RS09465
C675_RS09465 · HK · Classic
RefSeq: WP_021366764.1
UniProt: A0A069AHS9
GCF_000452325#C676_RS09485
C676_RS09485 · HK · Classic
RefSeq: WP_021366764.1
UniProt: A0A069AHS9
GCF_000473605#QSW_RS09520
QSW_RS09520 · HK · Classic
RefSeq: WP_021366764.1
UniProt: A0A069AHS9
GCF_000586575#Y779_RS0109345
Y779_RS0109345 · HK · Classic
RefSeq: WP_021366764.1
UniProt: A0A069AHS9
GCF_000939295#BN1097_RS10970
BN1097_RS10970 · HK · Classic
RefSeq: WP_021366764.1
UniProt: A0A069AHS9
GCF_001192735#AWU81_RS00070
AWU81_RS00070 · HK · Classic
RefSeq: WP_021366764.1
UniProt: A0A069AHS9
GCF_001263655#AWU80_RS00070
AWU80_RS00070 · HK · Classic
RefSeq: WP_021366764.1
UniProt: A0A069AHS9
GCF_001263675#AWU78_RS00135
AWU78_RS00135 · HK · Classic
RefSeq: WP_021366764.1
UniProt: A0A069AHS9
GCF_002301075#BGU05_RS17615
BGU05_RS17615 · HK · Classic
RefSeq: WP_021366764.1
UniProt: A0A069AHS9
GCF_002301105#BGU08_RS17685
BGU08_RS17685 · HK · Classic
RefSeq: WP_021366764.1
UniProt: A0A069AHS9
GCF_002302885#BGV09_RS15895
BGV09_RS15895 · HK · Classic
RefSeq: WP_021366764.1
UniProt: A0A069AHS9
GCF_002303125#BGV22_RS09355
BGV22_RS09355 · HK · Classic
RefSeq: WP_021366764.1
UniProt: A0A069AHS9
GCF_003481905#CDIF29688_RS10705
CDIF29688_RS10705 · HK · Classic
RefSeq: WP_021366764.1
UniProt: A0A069AHS9
GCF_004314925#E0O72_RS11930
E0O72_RS11930 · HK · Classic
RefSeq: WP_021366764.1
UniProt: A0A069AHS9
GCF_004315705#E0P69_RS09050
E0P69_RS09050 · HK · Classic
RefSeq: WP_021366764.1
UniProt: A0A069AHS9
GCF_004315945#E0P54_RS00605
E0P54_RS00605 · HK · Classic
RefSeq: WP_021366764.1
UniProt: A0A069AHS9
GCF_004316725#E0Q14_RS13300
E0Q14_RS13300 · HK · Classic
RefSeq: WP_021366764.1
UniProt: A0A069AHS9
GCF_004317945#E0Q65_RS05900
E0Q65_RS05900 · HK · Classic
RefSeq: WP_021366764.1
UniProt: A0A069AHS9
GCF_004318205#E0Q88_RS15720
E0Q88_RS15720 · HK · Classic
RefSeq: WP_021366764.1
UniProt: A0A069AHS9
GCF_004319125#E0R36_RS07600
E0R36_RS07600 · HK · Classic
RefSeq: WP_021366764.1
UniProt: A0A069AHS9
GCF_007000675#D1N83_RS16960
D1N83_RS16960 · HK · Classic
RefSeq: WP_021366764.1
UniProt: A0A069AHS9
GCF_007000845#D1N73_RS10320
D1N73_RS10320 · HK · Classic
RefSeq: WP_021366764.1
UniProt: A0A069AHS9
GCF_007000915#D1N70_RS14940
D1N70_RS14940 · HK · Classic
RefSeq: WP_021366764.1
UniProt: A0A069AHS9
GCF_007000925#D1N68_RS06635
D1N68_RS06635 · HK · Classic
RefSeq: WP_021366764.1
UniProt: A0A069AHS9
GCF_007000965#D1N69_RS06155
D1N69_RS06155 · HK · Classic
RefSeq: WP_021366764.1
UniProt: A0A069AHS9
GCF_007001195#D1N57_RS05745
D1N57_RS05745 · HK · Classic
RefSeq: WP_021366764.1
UniProt: A0A069AHS9
GCF_012030135#GSQ49_RS06795
GSQ49_RS06795 · HK · Classic
RefSeq: WP_021366764.1
UniProt: A0A069AHS9
GCF_017310965#JQS20_RS15315
JQS20_RS15315 · HK · Classic
RefSeq: WP_021366764.1
UniProt: A0A069AHS9
GCF_019426605#K1N11_RS17790
K1N11_RS17790 · HK · Classic
RefSeq: WP_021366764.1
UniProt: A0A069AHS9
GCF_021283725#LWE87_RS12775
LWE87_RS12775 · HK · Classic
RefSeq: WP_021366764.1
UniProt: A0A069AHS9
GCF_021283905#LWE93_RS09580
LWE93_RS09580 · HK · Classic
RefSeq: WP_021366764.1
UniProt: A0A069AHS9
GCF_021284005#LWE88_RS12630
LWE88_RS12630 · HK · Classic
RefSeq: WP_021366764.1
UniProt: A0A069AHS9
GCF_024451165#NO136_RS11310
NO136_RS11310 · HK · Classic
RefSeq: WP_021366764.1
UniProt: A0A069AHS9
GCF_025135955#CDIF104450_RS10510
CDIF104450_RS10510 · HK · Classic
RefSeq: WP_021366764.1
UniProt: A0A069AHS9
GCF_025533115#H3U19_RS14200
H3U19_RS14200 · HK · Classic
RefSeq: WP_021366764.1
UniProt: A0A069AHS9
GCF_026337815#OSC44_RS09070
OSC44_RS09070 · HK · Classic
RefSeq: WP_021366764.1
UniProt: A0A069AHS9
GCF_030251305#QQO58_RS03525
QQO58_RS03525 · HK · Classic
RefSeq: WP_021366764.1
UniProt: A0A069AHS9
GCF_030251745#QQO64_RS10975
QQO64_RS10975 · HK · Classic
RefSeq: WP_021366764.1
UniProt: A0A069AHS9
GCF_034188805#SQ131_RS10605
SQ131_RS10605 · HK · Classic
RefSeq: WP_021366764.1
UniProt: A0A069AHS9
GCF_036698425#LFB09_RS10890
LFB09_RS10890 · HK · Classic
RefSeq: WP_021366764.1
UniProt: A0A069AHS9
GCF_036698795#LFB08_RS11730
LFB08_RS11730 · HK · Classic
RefSeq: WP_021366764.1
UniProt: A0A069AHS9
GCF_043107605#ACGAK4_RS00045
ACGAK4_RS00045 · HK · Classic
RefSeq: WP_021366764.1
UniProt: A0A069AHS9
GCF_043107725#ACGAK8_RS13950
ACGAK8_RS13950 · HK · Classic
RefSeq: WP_021366764.1
UniProt: A0A069AHS9
GCF_900008635#A4001_RS16475
A4001_RS16475 · HK · Classic
RefSeq: WP_021366764.1
UniProt: A0A069AHS9
GCF_900009405#A4055_RS16155
A4055_RS16155 · HK · Classic
RefSeq: WP_021366764.1
UniProt: A0A069AHS9
GCF_900009805#A4Y97_RS04455
A4Y97_RS04455 · HK · Classic
RefSeq: WP_021366764.1
UniProt: A0A069AHS9

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_007001195
AssemblyASM700119v1 · Contighaploid
Genome composition4 189 649 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 98 · HK 45 · RR 51CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key