Gene detail

D1N57_RS05290

Histidine kinase, Classic

Clostridioides difficile · GCF_007001195

ClassHKTypeClassicLength343 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_007001195#D1N57_RS05290Stable P2CS identifier used across views.
GenomeGCF_007001195Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2827960Run 6 · 98 sequences · id 100% · cov 80%
External referencesWP_021366760.1 · A0A069ALH3 · MIST4 D1N57_RS05290RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length343 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage167 / 343 aa (48.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa343 aa
HisKA: 124-189 aa (66 aa)1HATPase_c: 241-341 aa (101 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
124-189 aa · 66 aa · 19.2% of protein
Raw tokenHisKA:124:0.000000278:189:66:64
2 HATPase_c#2
241-341 aa · 101 aa · 29.4% of protein
Raw tokenHATPase_c:241:5.39e-24:341:101:109
  • Raw architecture: HisKA:124:0.000000278:189:66:64#HATPase_c:241:5.39e-24:341:101:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_007001195::NZ_QWVD01000003.1::G00037
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span171841-173548Genomic interval covered by the local TCS group.
Identifiers
Old locus tagD1N57_05290RefSeq proteinWP_021366760.1
Context group IDGCF_007001195::NZ_QWVD01000003.1::G00037
Context members
D1N57_RS05290D1N57_RS05295
Partner locus tags
D1N57_RS05290D1N57_RS05295
Partner old locus tags
D1N57_05290D1N57_05295
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_021366760.1Primary protein accession used for annex mappings.
UniProt accessionA0A069ALH3Primary UniProt accession resolved in the annex database.
UniProt IDA0A069ALH3_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagD1N57_RS05290Primary locus identifier stored in the genes table.
Old locus tagD1N57_05290Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QWVD01000003.1Sequence record reported by the local genomic context database.
Genomic interval171 841-172 872 nt1 032 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span171 841-173 548 ntGCF_007001195::NZ_QWVD01000003.1::G00037

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_007001195::NZ_QWVD01000003.1::G00037

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QWVD01000003.1All displayed genes belong to this local TCS context.
Neighborhood span171 841-173 548 nt1 708 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
171 841 nt173 548 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

D1N57_RS05290GCF_007001195#D1N57_RS05290
HKClassicCurrent focus

171 841-172 872 nt · Reverse (-)

Old locus D1N57_05290RefSeq WP_021366760.1
D1N57_RS05295GCF_007001195#D1N57_RS05295
RROmpR

172 862-173 548 nt · Reverse (-)

Old locus D1N57_05295RefSeq WP_021362623.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2827960Run 6 · HK · 98 sequences
Representative sequenceGCF_000448765#QC5_RS09860Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2827960

Simplified PFAM architecture for HKOC_2827960

PFAM domain coverage: 173 / 343 aa (50.4%)

1 aa343 aa
HisKA: 124-189 aaHisKAHATPase_c: 236-342 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[124-189] | HATPase_c[236-342]
  • Domain count: 2
  • Matched identifier: HKOC_2827960
  • Positioned domains: HisKA 124-189 ; HATPase_c 236-342
Cluster members and taxonomy
Visualization

Representative gene: GCF_000448765#QC5_RS09860

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_007001195
AssemblyASM700119v1 · Contighaploid
Genome composition4 189 649 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 98 · HK 45 · RR 51CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key