1 HisKA#1
304-371 aa · 68 aa · 12.7% of protein
Raw token
HisKA:304:0.00000000000013:371:68:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
D1N66_RS03840
Histidine kinase, Classic
Clostridioides difficile · GCF_007001015
ClassHKTypeClassicLength535 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_007001015#D1N66_RS03840Stable P2CS identifier used across views.
GenomeGCF_007001015Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length535 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage178 / 535 aa (33.3%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa535 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
416-525 aa · 110 aa · 20.6% of protein
Raw token
HATPase_c:416:2.53e-31:525:110:109- Raw architecture: HisKA:304:0.00000000000013:371:68:64#HATPase_c:416:2.53e-31:525:110:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_007001015::NZ_QWUU01000038.1::G00028
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span5928-8230Genomic interval covered by the local TCS group.
Identifiers
Old locus tagD1N66_03845RefSeq proteinWP_003439079.1
Context group ID
GCF_007001015::NZ_QWUU01000038.1::G00028Context members
D1N66_RS03835D1N66_RS03840
Partner locus tags
D1N66_RS03835D1N66_RS03840
Partner old locus tags
D1N66_03840D1N66_03845
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003439079.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3MZ77Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3MZ77_CLODCDisplay identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagD1N66_RS03840Primary locus identifier stored in the genes table.
Old locus tagD1N66_03845Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QWUU01000038.1Sequence record reported by the local genomic context database.
Genomic interval6 623-8 230 nt1 608 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span5 928-8 230 ntGCF_007001015::NZ_QWUU01000038.1::G00028
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_007001015::NZ_QWUU01000038.1::G00028Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QWUU01000038.1All displayed genes belong to this local TCS context.
Neighborhood span5 928-8 230 nt2 303 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
5 928 nt8 230 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
D1N66_RS03835GCF_007001015#D1N66_RS03835
RROmpR
5 928-6 632 nt · Reverse (-)
D1N66_RS03840GCF_007001015#D1N66_RS03840
HKClassicCurrent focus
6 623-8 230 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000003215#QAC_RS0202670Use this link to inspect the representative gene detail.
PFAM architectureDUF4118 + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1338482
Simplified PFAM architecture for HKOC_1338482
PFAM domain coverage: 286 / 535 aa (53.5%)
1 aa535 aa
DUF4118HisKAHATPase_c
- Simplified architecture: DUF4118 + HisKA + HATPase_c
- Raw architecture: DUF4118[32-139] | HisKA[304-371] | HATPase_c[416-525]
- Domain count: 3
- Matched identifier: HKOC_1338482
- Positioned domains: DUF4118 32-139 ; HisKA 304-371 ; HATPase_c 416-525
Cluster members and taxonomy
Representative gene: GCF_000003215#QAC_RS0202670
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_007001015
AssemblyASM700101v1 · Contighaploid
Genome composition4 029 419 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 95 · HK 40 · RR 51CheA 1 · PP 4
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key