Gene detail

D1N74_RS03795

Histidine kinase, Hybrid

Clostridioides difficile · GCF_007000825

ClassHKTypeHybridLength852 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_007000825#D1N74_RS03795Stable P2CS identifier used across views.
GenomeGCF_007000825Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0484739Run 6 · 11 sequences · id 100% · cov 80%
External referencesWP_025992016.1 · MIST4 D1N74_RS03795RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_cResponse_reg
Protein length852 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage409 / 852 aa (48.0%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_c,2 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for D1N74_RS03795
Domain-by-domain annotation4 items
1 HisKA#1
344-410 aa · 67 aa · 7.9% of protein
Raw tokenHisKA:344:4.6e-18:410:67:64
2 HATPase_c#2
458-576 aa · 119 aa · 14.0% of protein
Raw tokenHATPase_c:458:5.96e-25:576:120:109
3 Response_reg#3
592-696 aa · 105 aa · 12.3% of protein
Raw tokenResponse_reg:592:3.54e-22:696:105:111
4 Response_reg#4
731-848 aa · 118 aa · 13.8% of protein
Raw tokenResponse_reg:731:6.24e-27:848:118:111
  • Raw architecture: HisKA:344:4.6e-18:410:67:64#HATPase_c:458:5.96e-25:576:120:109#Response_reg:592:3.54e-22:696:105:111#Response_reg:731:6.24e-27:848:118:111
  • Domain description: 1 HisKA,1 HATPase_c,2 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_007000825::NZ_QWUM01000027.1::G00028
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span11595-16163Genomic interval covered by the local TCS group.
Identifiers
Old locus tagD1N74_03795RefSeq proteinWP_025992016.1
Context group IDGCF_007000825::NZ_QWUM01000027.1::G00028
Context members
D1N74_RS03795D1N74_RS03805
Partner locus tags
D1N74_RS03795D1N74_RS03805
Partner old locus tags
D1N74_03795D1N74_03805
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_025992016.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagD1N74_RS03795Primary locus identifier stored in the genes table.
Old locus tagD1N74_03795Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QWUM01000027.1Sequence record reported by the local genomic context database.
Genomic interval11 595-14 153 nt2 559 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span11 595-16 163 ntGCF_007000825::NZ_QWUM01000027.1::G00028

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_007000825::NZ_QWUM01000027.1::G00028

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QWUM01000027.1All displayed genes belong to this local TCS context.
Neighborhood span11 595-16 163 nt4 569 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
11 595 nt16 163 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

D1N74_RS03795GCF_007000825#D1N74_RS03795
HKHybridCurrent focus

11 595-14 153 nt · Reverse (-)

Old locus D1N74_03795RefSeq WP_025992016.1
D1N74_RS03805GCF_007000825#D1N74_RS03805
RRRpfG

14 523-16 163 nt · Reverse (-)

Old locus D1N74_03805RefSeq WP_009901919.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0484739Run 6 · HK · 11 sequences
Representative sequenceGCF_000155025#UAB_RS0203450Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c + Response_reg + Response_reg4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0484739

Simplified PFAM architecture for HKOC_0484739

PFAM domain coverage: 413 / 852 aa (48.5%)

1 aa852 aa
HisKA: 344-410 aaHisKAHATPase_c: 458-575 aaHATPase_cResponse_reg: 592-702 aaResponse_regResponse_reg: 731-847 aaResponse_reg
HisKAHATPase_cResponse_regResponse_reg
  • Simplified architecture: HisKA + HATPase_c + Response_reg + Response_reg
  • Raw architecture: HisKA[344-410] | HATPase_c[458-575] | Response_reg[592-702] | Response_reg[731-847]
  • Domain count: 4
  • Matched identifier: HKOC_0484739
  • Positioned domains: HisKA 344-410 ; HATPase_c 458-575 ; Response_reg 592-702 ; Response_reg 731-847
Cluster members and taxonomy
Visualization

Representative gene: GCF_000155025#UAB_RS0203450

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_007000825
AssemblyASM700082v1 · Contighaploid
Genome composition4 145 098 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 100 · HK 47 · RR 52CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key