1 HisKA#1
230-293 aa · 64 aa · 14.0% of protein
Raw token
HisKA:230:0.00000000000173:293:64:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
D1N74_RS00350
Histidine kinase, Classic
Clostridioides difficile · GCF_007000825
ClassHKTypeClassicLength456 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_007000825#D1N74_RS00350Stable P2CS identifier used across views.
GenomeGCF_007000825Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length456 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage177 / 456 aa (38.8%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa456 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
343-455 aa · 113 aa · 24.8% of protein
Raw token
HATPase_c:343:6.29e-22:455:113:109- Raw architecture: HisKA:230:0.00000000000173:293:64:64#HATPase_c:343:6.29e-22:455:113:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_007000825::NZ_QWUM01000002.1::G00031
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span8485-10547Genomic interval covered by the local TCS group.
Identifiers
Old locus tagD1N74_00350RefSeq proteinWP_009901661.1
Context group ID
GCF_007000825::NZ_QWUM01000002.1::G00031Context members
D1N74_RS00345D1N74_RS00350
Partner locus tags
D1N74_RS00345D1N74_RS00350
Partner old locus tags
D1N74_00345D1N74_00350
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_009901661.1Primary protein accession used for annex mappings.
UniProt accessionA0AB74QD75Primary UniProt accession resolved in the annex database.
UniProt IDA0AB74QD75_CLODIDisplay identifier provided by UniProt.
GO / PubMed1 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagD1N74_RS00350Primary locus identifier stored in the genes table.
Old locus tagD1N74_00350Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QWUM01000002.1Sequence record reported by the local genomic context database.
Genomic interval9 177-10 547 nt1 371 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span8 485-10 547 ntGCF_007000825::NZ_QWUM01000002.1::G00031
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_007000825::NZ_QWUM01000002.1::G00031Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QWUM01000002.1All displayed genes belong to this local TCS context.
Neighborhood span8 485-10 547 nt2 063 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
8 485 nt10 547 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
D1N74_RS00345GCF_007000825#D1N74_RS00345
RROmpR
8 485-9 180 nt · Forward (+)
D1N74_RS00350GCF_007000825#D1N74_RS00350
HKClassicCurrent focus
9 177-10 547 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000155025#UAB_RS0201840Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1887710
Simplified PFAM architecture for HKOC_1887710
PFAM domain coverage: 176 / 456 aa (38.6%)
1 aa456 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[230-293] | HATPase_c[343-454]
- Domain count: 2
- Matched identifier: HKOC_1887710
- Positioned domains: HisKA 230-293 ; HATPase_c 343-454
Cluster members and taxonomy
Representative gene: GCF_000155025#UAB_RS0201840
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_007000825
AssemblyASM700082v1 · Contighaploid
Genome composition4 145 098 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 100 · HK 47 · RR 52CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key