Gene detail

D1N76_RS19135

Histidine kinase, Classic

Clostridioides difficile · GCF_007000785

ClassHKTypeClassicLength337 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_007000785#D1N76_RS19135Stable P2CS identifier used across views.
GenomeGCF_007000785Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2557911Run 6 · 214 sequences · id 100% · cov 80%
External referencesWP_142822098.1 · MIST4 D1N76_RS19135RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length337 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage228 / 337 aa (67.7%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa337 aa
HAMP: 35-103 aa (69 aa)1HisKA: 115-168 aa (54 aa)2HATPase_c: 229-333 aa (105 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
35-103 aa · 69 aa · 20.5% of protein
Raw tokenHAMP:35:0.000000404:103:70:69
2 HisKA#2
115-168 aa · 54 aa · 16.0% of protein
Raw tokenHisKA:115:0.0000000428:168:54:64
3 HATPase_c#3
229-333 aa · 105 aa · 31.2% of protein
Raw tokenHATPase_c:229:3.12e-20:333:106:109
  • Raw architecture: HAMP:35:0.000000404:103:70:69#HisKA:115:0.0000000428:168:54:64#HATPase_c:229:3.12e-20:333:106:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_007000785::NZ_QWUK01000852.1::G00051
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span186-1199Genomic interval covered by the local TCS group.
Identifiers
Old locus tagD1N76_19195RefSeq proteinWP_142822098.1
Context group IDGCF_007000785::NZ_QWUK01000852.1::G00051
Context members
D1N76_RS19135
Partner locus tags
D1N76_RS19135
Partner old locus tags
D1N76_19195
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_142822098.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagD1N76_RS19135Primary locus identifier stored in the genes table.
Old locus tagD1N76_19195Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QWUK01000852.1Sequence record reported by the local genomic context database.
Genomic interval186-1 199 nt1 014 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span186-1 199 ntGCF_007000785::NZ_QWUK01000852.1::G00051

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_007000785::NZ_QWUK01000852.1::G00051

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QWUK01000852.1All displayed genes belong to this local TCS context.
Neighborhood span186-1 199 nt1 014 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
186 nt1 199 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

D1N76_RS19135GCF_007000785#D1N76_RS19135
HKClassicCurrent focus

186-1 199 nt · Reverse (-)

Old locus D1N76_19195RefSeq WP_142822098.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2557911Run 6 · HK · 214 sequences
Representative sequenceGCF_000448805#QKI_RS02875Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2557911

Simplified PFAM architecture for HKOC_2557911

PFAM domain coverage: 219 / 386 aa (56.7%)

1 aa386 aa
HAMP: 106-151 aaHAMPHisKA: 164-231 aaHisKAHATPase_c: 278-382 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[106-151] | HisKA[164-231] | HATPase_c[278-382]
  • Domain count: 3
  • Matched identifier: HKOC_2557911
  • Positioned domains: HAMP 106-151 ; HisKA 164-231 ; HATPase_c 278-382
Cluster members and taxonomy
Visualization

Representative gene: GCF_000448805#QKI_RS02875

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_007000785
AssemblyASM700078v1 · Contighaploid
Genome composition4 119 768 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 91 · HK 36 · RR 50CheA 1 · PP 5
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key