Gene detail

D1N76_RS16510

Histidine kinase, Classic

Clostridioides difficile · GCF_007000785

ClassHKTypeClassicLength479 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_007000785#D1N76_RS16510Stable P2CS identifier used across views.
GenomeGCF_007000785Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0405628Run 6 · 94 sequences · id 100% · cov 80%
External referencesWP_142821973.1 · MIST4 D1N76_RS16510RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

GAF_3HisKAHATPase_c
Protein length479 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage305 / 479 aa (63.7%)Merged over positioned domains only.
Domain description1 GAF_3,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa479 aa
GAF_3: 112-235 aa (124 aa)1HisKA: 255-322 aa (68 aa)2HATPase_c: 366-478 aa (113 aa)3
Domain-by-domain annotation3 items
1 GAF_3#1
112-235 aa · 124 aa · 25.9% of protein
Raw tokenGAF_3:112:0.00000268:235:129:129
2 HisKA#2
255-322 aa · 68 aa · 14.2% of protein
Raw tokenHisKA:255:0.0000000000033:322:68:64
3 HATPase_c#3
366-478 aa · 113 aa · 23.6% of protein
Raw tokenHATPase_c:366:1.19e-30:478:113:109
  • Raw architecture: GAF_3:112:0.00000268:235:129:129#HisKA:255:0.0000000000033:322:68:64#HATPase_c:366:1.19e-30:478:113:109
  • Domain description: 1 GAF_3,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_007000785::NZ_QWUK01000568.1::G00033
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1-2174Genomic interval covered by the local TCS group.
Identifiers
Old locus tagD1N76_16550RefSeq proteinWP_142821973.1
Context group IDGCF_007000785::NZ_QWUK01000568.1::G00033
Context members
D1N76_RS16510D1N76_RS16515
Partner locus tags
D1N76_RS16510D1N76_RS16515
Partner old locus tags
D1N76_16550D1N76_16555
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_142821973.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagD1N76_RS16510Primary locus identifier stored in the genes table.
Old locus tagD1N76_16550Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QWUK01000568.1Sequence record reported by the local genomic context database.
Genomic interval1-1 442 nt1 442 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1-2 174 ntGCF_007000785::NZ_QWUK01000568.1::G00033

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_007000785::NZ_QWUK01000568.1::G00033

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QWUK01000568.1All displayed genes belong to this local TCS context.
Neighborhood span1-2 174 nt2 174 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 nt2 174 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

D1N76_RS16515GCF_007000785#D1N76_RS16515
RROmpR

1 476-2 174 nt · Forward (+)

Old locus D1N76_16555RefSeq WP_021364519.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0405628Run 6 · HK · 94 sequences
Representative sequenceGCF_000009205#CD630_RS09955Use this link to inspect the representative gene detail.
PFAM architectureKdpD + DUF4118 + HisKA + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0405628

Simplified PFAM architecture for HKOC_0405628

PFAM domain coverage: 494 / 900 aa (54.9%)

1 aa900 aa
KdpD: 22-230 aaKdpDDUF4118: 409-514 aaDUF4118HisKA: 676-743 aaHisKAHATPase_c: 788-898 aaHATPase_c
KdpDDUF4118HisKAHATPase_c
  • Simplified architecture: KdpD + DUF4118 + HisKA + HATPase_c
  • Raw architecture: KdpD[22-230] | DUF4118[409-514] | HisKA[676-743] | HATPase_c[788-898]
  • Domain count: 4
  • Matched identifier: HKOC_0405628
  • Positioned domains: KdpD 22-230 ; DUF4118 409-514 ; HisKA 676-743 ; HATPase_c 788-898
Cluster members and taxonomy
Visualization

Representative gene: GCF_000009205#CD630_RS09955

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_007000785
AssemblyASM700078v1 · Contighaploid
Genome composition4 119 768 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 91 · HK 36 · RR 50CheA 1 · PP 5
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key