Gene detail

D1N76_RS09005

Histidine kinase, Classic

Clostridioides difficile · GCF_007000785

ClassHKTypeClassicLength664 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_007000785#D1N76_RS09005Stable P2CS identifier used across views.
GenomeGCF_007000785Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0860239Run 6 · 584 sequences · id 100% · cov 80%
External referencesWP_004454411.1 · A0A6N3HCM1 · MIST4 D1N76_RS09005RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

SBP_bac_3HisKAHATPase_c
Protein length664 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage386 / 664 aa (58.1%)Merged over positioned domains only.
Domain description1 SBP_bac_3,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa664 aa
SBP_bac_3: 58-278 aa (221 aa)1HisKA: 446-508 aa (63 aa)2HATPase_c: 557-658 aa (102 aa)3
Domain-by-domain annotation3 items
1 SBP_bac_3#1
58-278 aa · 221 aa · 33.3% of protein
Raw tokenSBP_bac_3:58:1.8e-41:278:230:224
2 HisKA#2
446-508 aa · 63 aa · 9.5% of protein
Raw tokenHisKA:446:0.0000000000000416:508:63:64
3 HATPase_c#3
557-658 aa · 102 aa · 15.4% of protein
Raw tokenHATPase_c:557:5.02e-23:658:104:109
  • Raw architecture: SBP_bac_3:58:1.8e-41:278:230:224#HisKA:446:0.0000000000000416:508:63:64#HATPase_c:557:5.02e-23:658:104:109
  • Domain description: 1 SBP_bac_3,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_007000785::NZ_QWUK01000172.1::G00009
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span3484-6631Genomic interval covered by the local TCS group.
Identifiers
Old locus tagD1N76_09025RefSeq proteinWP_004454411.1
Context group IDGCF_007000785::NZ_QWUK01000172.1::G00009
Context members
D1N76_RS09005D1N76_RS09010
Partner locus tags
D1N76_RS09005D1N76_RS09010
Partner old locus tags
D1N76_09025D1N76_09030
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_004454411.1Primary protein accession used for annex mappings.
UniProt accessionA0A6N3HCM1Primary UniProt accession resolved in the annex database.
UniProt IDA0A6N3HCM1_CLODIDisplay identifier provided by UniProt.
GO / PubMed2 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagD1N76_RS09005Primary locus identifier stored in the genes table.
Old locus tagD1N76_09025Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QWUK01000172.1Sequence record reported by the local genomic context database.
Genomic interval3 484-5 478 nt1 995 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span3 484-6 631 ntGCF_007000785::NZ_QWUK01000172.1::G00009

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_007000785::NZ_QWUK01000172.1::G00009

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QWUK01000172.1All displayed genes belong to this local TCS context.
Neighborhood span3 484-6 631 nt3 148 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
3 484 nt6 631 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

D1N76_RS09005GCF_007000785#D1N76_RS09005
HKClassicCurrent focus

3 484-5 478 nt · Forward (+)

Old locus D1N76_09025RefSeq WP_004454411.1
D1N76_RS09010GCF_007000785#D1N76_RS09010
RRunclassified

5 478-6 631 nt · Forward (+)

Old locus D1N76_09030RefSeq WP_142799985.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0860239Run 6 · HK · 584 sequences
Representative sequenceGCF_000155025#UAB_RS0209915Use this link to inspect the representative gene detail.
PFAM architectureSBP_bac_3 + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0860239

Simplified PFAM architecture for HKOC_0860239

PFAM domain coverage: 385 / 664 aa (58.0%)

1 aa664 aa
SBP_bac_3: 60-277 aaSBP_bac_3HisKA: 448-509 aaHisKAHATPase_c: 555-659 aaHATPase_c
SBP_bac_3HisKAHATPase_c
  • Simplified architecture: SBP_bac_3 + HisKA + HATPase_c
  • Raw architecture: SBP_bac_3[60-277] | HisKA[448-509] | HATPase_c[555-659]
  • Domain count: 3
  • Matched identifier: HKOC_0860239
  • Positioned domains: SBP_bac_3 60-277 ; HisKA 448-509 ; HATPase_c 555-659
Cluster members and taxonomy
Visualization

Representative gene: GCF_000155025#UAB_RS0209915

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_007000785
AssemblyASM700078v1 · Contighaploid
Genome composition4 119 768 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 91 · HK 36 · RR 50CheA 1 · PP 5
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key