Gene detail

D1N85_RS12145

Histidine kinase, Classic

Clostridioides difficile · GCF_007000615

ClassHKTypeClassicLength421 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_007000615#D1N85_RS12145Stable P2CS identifier used across views.
GenomeGCF_007000615Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2215987Run 6 · 1668 sequences · id 100% · cov 80%
External referencesWP_142797975.1 · MIST4 D1N85_RS12145RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length421 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage180 / 421 aa (42.8%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa421 aa
HisKA: 196-260 aa (65 aa)1HATPase_c: 307-421 aa (115 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
196-260 aa · 65 aa · 15.4% of protein
Raw tokenHisKA:196:0.0000000000175:260:65:64
2 HATPase_c#2
307-421 aa · 115 aa · 27.3% of protein
Raw tokenHATPase_c:307:3.91e-18:421:118:109
  • Raw architecture: HisKA:196:0.0000000000175:260:65:64#HATPase_c:307:3.91e-18:421:118:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_007000615::NZ_QWUB01000281.1::G00021
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1-1914Genomic interval covered by the local TCS group.
Identifiers
Old locus tagD1N85_12145RefSeq proteinWP_142797975.1
Context group IDGCF_007000615::NZ_QWUB01000281.1::G00021
Context members
D1N85_RS12145D1N85_RS12150
Partner locus tags
D1N85_RS12145D1N85_RS12150
Partner old locus tags
D1N85_12145D1N85_12150
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_142797975.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagD1N85_RS12145Primary locus identifier stored in the genes table.
Old locus tagD1N85_12145Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QWUB01000281.1Sequence record reported by the local genomic context database.
Genomic interval1-1 262 nt1 262 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span1-1 914 ntGCF_007000615::NZ_QWUB01000281.1::G00021

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_007000615::NZ_QWUB01000281.1::G00021

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QWUB01000281.1All displayed genes belong to this local TCS context.
Neighborhood span1-1 914 nt1 914 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 nt1 914 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

D1N85_RS12150GCF_007000615#D1N85_RS12150
RROmpR

1 246-1 914 nt · Reverse (-)

Old locus D1N85_12150RefSeq WP_003424455.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2215987Run 6 · HK · 1668 sequences
Representative sequenceGCF_000009205#CD630_RS11460Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2215987

Simplified PFAM architecture for HKOC_2215987

PFAM domain coverage: 179 / 425 aa (42.1%)

1 aa425 aa
HisKA: 197-260 aaHisKAHATPase_c: 308-422 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[197-260] | HATPase_c[308-422]
  • Domain count: 2
  • Matched identifier: HKOC_2215987
  • Positioned domains: HisKA 197-260 ; HATPase_c 308-422
Cluster members and taxonomy
Visualization

Representative gene: GCF_000009205#CD630_RS11460

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_007000615
AssemblyASM700061v1 · Contighaploid
Genome composition4 069 384 bp · 29,5% GCClostridioides difficile
Signal transduction countsGenes 101 · HK 45 · RR 52CheA 1 · PP 4
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key