Gene detail

EWM32_RS10235

Histidine kinase, Classic

Clostridioides difficile · GCF_007000575

ClassHKTypeClassicLength334 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_007000575#EWM32_RS10235Stable P2CS identifier used across views.
GenomeGCF_007000575Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2849797Run 6 · 55 sequences · id 100% · cov 80%
External referencesWP_016728538.1 · MIST4 EWM32_RS10235RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length334 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage169 / 334 aa (50.6%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for EWM32_RS10235
Domain-by-domain annotation2 items
1 HisKA#1
118-178 aa · 61 aa · 18.3% of protein
Raw tokenHisKA:118:0.00000708:178:63:64
2 HATPase_c#2
224-331 aa · 108 aa · 32.3% of protein
Raw tokenHATPase_c:224:2.81e-25:331:108:109
  • Raw architecture: HisKA:118:0.00000708:178:63:64#HATPase_c:224:2.81e-25:331:108:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_007000575::NZ_SERE01000006.1::G00046
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span195301-197003Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEWM32_10235RefSeq proteinWP_016728538.1
Context group IDGCF_007000575::NZ_SERE01000006.1::G00046
Context members
EWM32_RS10230EWM32_RS10235
Partner locus tags
EWM32_RS10230EWM32_RS10235
Partner old locus tags
EWM32_10230EWM32_10235
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_016728538.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagEWM32_RS10235Primary locus identifier stored in the genes table.
Old locus tagEWM32_10235Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_SERE01000006.1Sequence record reported by the local genomic context database.
Genomic interval195 999-197 003 nt1 005 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span195 301-197 003 ntGCF_007000575::NZ_SERE01000006.1::G00046

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_007000575::NZ_SERE01000006.1::G00046

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_SERE01000006.1All displayed genes belong to this local TCS context.
Neighborhood span195 301-197 003 nt1 703 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
195 301 nt197 003 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

EWM32_RS10230GCF_007000575#EWM32_RS10230
RROmpR

195 301-195 975 nt · Forward (+)

Old locus EWM32_10230RefSeq WP_003436727.1
EWM32_RS10235GCF_007000575#EWM32_RS10235
HKClassicCurrent focus

195 999-197 003 nt · Forward (+)

Old locus EWM32_10235RefSeq WP_016728538.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2849797Run 6 · HK · 55 sequences
Representative sequenceGCF_000242355#MUI_RS0101795Use this link to inspect the representative gene detail.
PFAM architectureHATPase_c1 domain in the representative PFAM annotation.

PFAM architecture for HKOC_2849797

Simplified PFAM architecture for HKOC_2849797

PFAM domain coverage: 108 / 334 aa (32.3%)

1 aa334 aa
HATPase_c: 224-331 aaHATPase_c
HATPase_c
  • Simplified architecture: HATPase_c
  • Raw architecture: HATPase_c[224-331]
  • Domain count: 1
  • Matched identifier: HKOC_2849797
  • Positioned domains: HATPase_c 224-331
Cluster members and taxonomy
Visualization

Representative gene: GCF_000242355#MUI_RS0101795

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_007000575
AssemblyASM700057v1 · Contighaploid
Genome composition4 121 174 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 101 · HK 48 · RR 52CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key