1 HisKA#1
85-150 aa · 66 aa · 21.6% of protein
Raw token
HisKA:85:0.0000000591:150:66:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
EWM36_RS18290
Histidine kinase, Classic
Clostridioides difficile · GCF_007000505
ClassHKTypeClassicLength305 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_007000505#EWM36_RS18290Stable P2CS identifier used across views.
GenomeGCF_007000505Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length305 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage175 / 305 aa (57.4%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa305 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
197-305 aa · 109 aa · 35.7% of protein
Raw token
HATPase_c:197:4.48e-31:305:109:109- Raw architecture: HisKA:85:0.0000000591:150:66:64#HATPase_c:197:4.48e-31:305:109:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_007000505::NZ_SERI01000070.1::G00048
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span3971-5587Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEWM36_18330RefSeq proteinWP_011861096.1
Context group ID
GCF_007000505::NZ_SERI01000070.1::G00048Context members
EWM36_RS18290EWM36_RS18295
Partner locus tags
EWM36_RS18290EWM36_RS18295
Partner old locus tags
EWM36_18330EWM36_18335
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_011861096.1Primary protein accession used for annex mappings.
UniProt accessionA0A4P9CFA0Primary UniProt accession resolved in the annex database.
UniProt IDA0A4P9CFA0_EUBMLDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagEWM36_RS18290Primary locus identifier stored in the genes table.
Old locus tagEWM36_18330Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_SERI01000070.1Sequence record reported by the local genomic context database.
Genomic interval3 971-4 888 nt918 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span3 971-5 587 ntGCF_007000505::NZ_SERI01000070.1::G00048
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_007000505::NZ_SERI01000070.1::G00048Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_SERI01000070.1All displayed genes belong to this local TCS context.
Neighborhood span3 971-5 587 nt1 617 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
3 971 nt5 587 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
EWM36_RS18290GCF_007000505#EWM36_RS18290
HKClassicCurrent focus
3 971-4 888 nt · Reverse (-)
EWM36_RS18295GCF_007000505#EWM36_RS18295
RROmpR
4 895-5 587 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000009205#CD630_RS06130Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2881988
Simplified PFAM architecture for HKOC_2881988
PFAM domain coverage: 172 / 305 aa (56.4%)
1 aa305 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[85-148] | HATPase_c[197-304]
- Domain count: 2
- Matched identifier: HKOC_2881988
- Positioned domains: HisKA 85-148 ; HATPase_c 197-304
Cluster members and taxonomy
Representative gene: GCF_000009205#CD630_RS06130
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_007000505
AssemblyASM700050v1 · Contighaploid
Genome composition4 128 982 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 101 · HK 48 · RR 52CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key