Gene detail

EWM36_RS08810

Histidine kinase, Classic

Clostridioides difficile · GCF_007000505

ClassHKTypeClassicLength360 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_007000505#EWM36_RS08810Stable P2CS identifier used across views.
GenomeGCF_007000505Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2747088Run 6 · 193 sequences · id 100% · cov 80%
External referencesWP_021403563.1 · MIST4 EWM36_RS08810RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length360 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage161 / 360 aa (44.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa360 aa
HisKA: 135-198 aa (64 aa)1HATPase_c: 248-344 aa (97 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
135-198 aa · 64 aa · 17.8% of protein
Raw tokenHisKA:135:0.000000000000315:198:64:64
2 HATPase_c#2
248-344 aa · 97 aa · 26.9% of protein
Raw tokenHATPase_c:248:4.3e-21:344:97:109
  • Raw architecture: HisKA:135:0.000000000000315:198:64:64#HATPase_c:248:4.3e-21:344:97:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_007000505::NZ_SERI01000011.1::G00002
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span74223-76056Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEWM36_08810RefSeq proteinWP_021403563.1
Context group IDGCF_007000505::NZ_SERI01000011.1::G00002
Context members
EWM36_RS08805EWM36_RS08810
Partner locus tags
EWM36_RS08805EWM36_RS08810
Partner old locus tags
EWM36_08805EWM36_08810
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021403563.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagEWM36_RS08810Primary locus identifier stored in the genes table.
Old locus tagEWM36_08810Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_SERI01000011.1Sequence record reported by the local genomic context database.
Genomic interval74 974-76 056 nt1 083 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span74 223-76 056 ntGCF_007000505::NZ_SERI01000011.1::G00002

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_007000505::NZ_SERI01000011.1::G00002

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_SERI01000011.1All displayed genes belong to this local TCS context.
Neighborhood span74 223-76 056 nt1 834 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
74 223 nt76 056 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

EWM36_RS08805GCF_007000505#EWM36_RS08805
RROmpR

74 223-74 924 nt · Forward (+)

Old locus EWM36_08805RefSeq WP_003436401.1
EWM36_RS08810GCF_007000505#EWM36_RS08810
HKClassicCurrent focus

74 974-76 056 nt · Forward (+)

Old locus EWM36_08810RefSeq WP_021403563.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2747088Run 6 · HK · 193 sequences
Representative sequenceGCF_000242355#MUI_RS0107365Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2747088

Simplified PFAM architecture for HKOC_2747088

PFAM domain coverage: 161 / 360 aa (44.7%)

1 aa360 aa
HisKA: 136-198 aaHisKAHATPase_c: 248-345 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[136-198] | HATPase_c[248-345]
  • Domain count: 2
  • Matched identifier: HKOC_2747088
  • Positioned domains: HisKA 136-198 ; HATPase_c 248-345
Cluster members and taxonomy
Visualization

Representative gene: GCF_000242355#MUI_RS0107365

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_007000505
AssemblyASM700050v1 · Contighaploid
Genome composition4 128 982 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 101 · HK 48 · RR 52CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key