1 HisKA#1
218-282 aa · 65 aa · 14.8% of protein
Raw token
HisKA:218:0.000000000291:282:65:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
EWL72_RS00945
Histidine kinase, Classic
Clostridioides difficile · GCF_007000385
ClassHKTypeClassicLength440 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_007000385#EWL72_RS00945Stable P2CS identifier used across views.
GenomeGCF_007000385Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length440 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage165 / 440 aa (37.5%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa440 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
338-437 aa · 100 aa · 22.7% of protein
Raw token
HATPase_c:338:8.49e-25:437:100:109- Raw architecture: HisKA:218:0.000000000291:282:65:64#HATPase_c:338:8.49e-25:437:100:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_007000385::NZ_SERN01000001.1::G00020
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span216389-218412Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEWL72_00945RefSeq proteinWP_185722295.1
Context group ID
GCF_007000385::NZ_SERN01000001.1::G00020Context members
EWL72_RS00940EWL72_RS00945
Partner locus tags
EWL72_RS00940EWL72_RS00945
Partner old locus tags
EWL72_00940EWL72_00945
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_185722295.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagEWL72_RS00945Primary locus identifier stored in the genes table.
Old locus tagEWL72_00945Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_SERN01000001.1Sequence record reported by the local genomic context database.
Genomic interval217 090-218 412 nt1 323 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span216 389-218 412 ntGCF_007000385::NZ_SERN01000001.1::G00020
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_007000385::NZ_SERN01000001.1::G00020Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_SERN01000001.1All displayed genes belong to this local TCS context.
Neighborhood span216 389-218 412 nt2 024 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
216 389 nt218 412 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
EWL72_RS00940GCF_007000385#EWL72_RS00940
RROmpR
216 389-217 096 nt · Forward (+)
EWL72_RS00945GCF_007000385#EWL72_RS00945
HKClassicCurrent focus
217 090-218 412 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_003863255#EGL89_RS00720Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2074353
Simplified PFAM architecture for HKOC_2074353
PFAM domain coverage: 170 / 440 aa (38.6%)
1 aa440 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[217-282] | HATPase_c[334-437]
- Domain count: 2
- Matched identifier: HKOC_2074353
- Positioned domains: HisKA 217-282 ; HATPase_c 334-437
Cluster members and taxonomy
Representative gene: GCF_003863255#EGL89_RS00720
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_007000385
AssemblyASM700038v1 · Contighaploid
Genome composition4 186 862 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 103 · HK 49 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key