1 HisKA#1
245-313 aa · 69 aa · 14.8% of protein
Raw token
HisKA:245:0.000000000000185:313:69:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
EWL75_RS06180
Histidine kinase, Classic
Clostridioides difficile · GCF_007000295
ClassHKTypeClassicLength467 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_007000295#EWL75_RS06180Stable P2CS identifier used across views.
GenomeGCF_007000295Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length467 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage176 / 467 aa (37.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa467 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
360-466 aa · 107 aa · 22.9% of protein
Raw token
HATPase_c:360:1.12e-27:466:108:109- Raw architecture: HisKA:245:0.000000000000185:313:69:64#HATPase_c:360:1.12e-27:466:108:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_007000295::NZ_SERQ01000003.1::G00030
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span200777-202180Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEWL75_06180RefSeq proteinWP_021377440.1
Context group ID
GCF_007000295::NZ_SERQ01000003.1::G00030Context members
EWL75_RS06180
Partner locus tags
EWL75_RS06180
Partner old locus tags
EWL75_06180
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_021377440.1Primary protein accession used for annex mappings.
UniProt accessionA0A9X8RGV0Primary UniProt accession resolved in the annex database.
UniProt IDA0A9X8RGV0_CLODIDisplay identifier provided by UniProt.
GO / PubMed1 / 1Unique GO terms and literature references available below.
Reference hubs
GO terms
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagEWL75_RS06180Primary locus identifier stored in the genes table.
Old locus tagEWL75_06180Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_SERQ01000003.1Sequence record reported by the local genomic context database.
Genomic interval200 777-202 180 nt1 404 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span200 777-202 180 ntGCF_007000295::NZ_SERQ01000003.1::G00030
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_007000295::NZ_SERQ01000003.1::G00030Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_SERQ01000003.1All displayed genes belong to this local TCS context.
Neighborhood span200 777-202 180 nt1 404 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
200 777 nt202 180 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
EWL75_RS06180GCF_007000295#EWL75_RS06180
HKClassicCurrent focus
200 777-202 180 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000448745#QC1_RS10400Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1748386
Simplified PFAM architecture for HKOC_1748386
PFAM domain coverage: 167 / 467 aa (35.8%)
1 aa467 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[245-306] | HATPase_c[362-466]
- Domain count: 2
- Matched identifier: HKOC_1748386
- Positioned domains: HisKA 245-306 ; HATPase_c 362-466
Cluster members and taxonomy
Representative gene: GCF_000448745#QC1_RS10400
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_007000295
AssemblyASM700029v1 · Contighaploid
Genome composition4 187 108 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 103 · HK 49 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key