Gene detail

DA411_RS15840

Histidine kinase, Classic

Clostridioides difficile · GCF_006408335

ClassHKTypeClassicLength336 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_006408335#DA411_RS15840Stable P2CS identifier used across views.
GenomeGCF_006408335Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2783894Run 6 · 9 sequences · id 100% · cov 80%
External referencesWP_235675336.1 · MIST4 DA411_RS15840RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length336 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage235 / 336 aa (69.9%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa336 aa
HAMP: 33-100 aa (68 aa)1HisKA: 121-184 aa (64 aa)2HATPase_c: 234-336 aa (103 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
33-100 aa · 68 aa · 20.2% of protein
Raw tokenHAMP:33:0.000000000512:100:70:69
2 HisKA#2
121-184 aa · 64 aa · 19.0% of protein
Raw tokenHisKA:121:0.00000000636:184:64:64
3 HATPase_c#3
234-336 aa · 103 aa · 30.7% of protein
Raw tokenHATPase_c:234:3.27e-17:336:106:109
  • Raw architecture: HAMP:33:0.000000000512:100:70:69#HisKA:121:0.00000000636:184:64:64#HATPase_c:234:3.27e-17:336:106:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_006408335::NZ_PZOS01000003.1::G00054
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span3292478-3294264Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDA411_15845RefSeq proteinWP_235675336.1
Context group IDGCF_006408335::NZ_PZOS01000003.1::G00054
Context members
DA411_RS15840DA411_RS15845
Partner locus tags
DA411_RS15840DA411_RS15845
Partner old locus tags
DA411_15845DA411_15850
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_235675336.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDA411_RS15840Primary locus identifier stored in the genes table.
Old locus tagDA411_15845Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_PZOS01000003.1Sequence record reported by the local genomic context database.
Genomic interval3 292 478-3 293 488 nt1 011 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span3 292 478-3 294 264 ntGCF_006408335::NZ_PZOS01000003.1::G00054

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_006408335::NZ_PZOS01000003.1::G00054

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_PZOS01000003.1All displayed genes belong to this local TCS context.
Neighborhood span3 292 478-3 294 264 nt1 787 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
3 292 478 nt3 294 264 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DA411_RS15840GCF_006408335#DA411_RS15840
HKClassicCurrent focus

3 292 478-3 293 488 nt · Reverse (-)

Old locus DA411_15845RefSeq WP_235675336.1
DA411_RS15845GCF_006408335#DA411_RS15845
RROmpR

3 293 596-3 294 264 nt · Reverse (-)

Old locus DA411_15850RefSeq WP_074137600.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2783894Run 6 · HK · 9 sequences
Representative sequenceGCF_900164815#B2A40_RS03885Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2783894

Simplified PFAM architecture for HKOC_2783894

PFAM domain coverage: 166 / 354 aa (46.9%)

1 aa354 aa
HisKA: 139-202 aaHisKAHATPase_c: 252-353 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[139-202] | HATPase_c[252-353]
  • Domain count: 2
  • Matched identifier: HKOC_2783894
  • Positioned domains: HisKA 139-202 ; HATPase_c 252-353
Cluster members and taxonomy
Visualization

Representative gene: GCF_900164815#B2A40_RS03885

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_006408335
AssemblyASM640833v1 · Contighaploid
Genome composition4 361 487 bp · 29,5% GCClostridioides difficile
Signal transduction countsGenes 113 · HK 54 · RR 59CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key