1 HisKA#1
89-144 aa · 56 aa · 19.0% of protein
Raw token
HisKA:89:0.000000000018:144:56:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
DA411_RS12110
Histidine kinase, Classic
Clostridioides difficile · GCF_006408335
ClassHKTypeClassicLength295 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_006408335#DA411_RS12110Stable P2CS identifier used across views.
GenomeGCF_006408335Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length295 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage142 / 295 aa (48.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa295 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
196-281 aa · 86 aa · 29.2% of protein
Raw token
HATPase_c:196:0.00000000000000256:281:91:109- Raw architecture: HisKA:89:0.000000000018:144:56:64#HATPase_c:196:0.00000000000000256:281:91:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_006408335::NZ_PZOS01000003.1::G00042
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span2449652-2450539Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDA411_12105RefSeq proteinWP_021739603.1
Context group ID
GCF_006408335::NZ_PZOS01000003.1::G00042Context members
DA411_RS12110
Partner locus tags
DA411_RS12110
Partner old locus tags
DA411_12105
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_021739603.1Primary protein accession used for annex mappings.
UniProt accessionU2Q5S2Primary UniProt accession resolved in the annex database.
UniProt IDU2Q5S2_EUBRADisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagDA411_RS12110Primary locus identifier stored in the genes table.
Old locus tagDA411_12105Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_PZOS01000003.1Sequence record reported by the local genomic context database.
Genomic interval2 449 652-2 450 539 nt888 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span2 449 652-2 450 539 ntGCF_006408335::NZ_PZOS01000003.1::G00042
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_006408335::NZ_PZOS01000003.1::G00042Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_PZOS01000003.1All displayed genes belong to this local TCS context.
Neighborhood span2 449 652-2 450 539 nt888 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 449 652 nt2 450 539 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
DA411_RS12110GCF_006408335#DA411_RS12110
HKClassicCurrent focus
2 449 652-2 450 539 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_964272115#ACFY56_RS13685Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2892170
Simplified PFAM architecture for HKOC_2892170
PFAM domain coverage: 144 / 296 aa (48.6%)
1 aa296 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[88-145] | HATPase_c[197-282]
- Domain count: 2
- Matched identifier: HKOC_2892170
- Positioned domains: HisKA 88-145 ; HATPase_c 197-282
Cluster members and taxonomy
Representative gene: GCF_964272115#ACFY56_RS13685
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_006408335
AssemblyASM640833v1 · Contighaploid
Genome composition4 361 487 bp · 29,5% GCClostridioides difficile
Signal transduction countsGenes 113 · HK 54 · RR 59CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key