Gene detail

DA404_RS09850

Histidine kinase, Classic

Clostridioides difficile · GCF_006408325

ClassHKTypeClassicLength462 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_006408325#DA404_RS09850Stable P2CS identifier used across views.
GenomeGCF_006408325Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1811307Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_330574846.1 · MIST4 DA404_RS09850RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

H_kinase_NHisKA_2HATPase_c
Protein length462 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage304 / 462 aa (65.8%)Merged over positioned domains only.
Domain description1 H_kinase_N,1 HisKA_2,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa462 aa
H_kinase_N: 5-135 aa (131 aa)1HisKA_2: 269-343 aa (75 aa)2HATPase_c: 363-460 aa (98 aa)3
Domain-by-domain annotation3 items
1 H_kinase_N#1
5-135 aa · 131 aa · 28.4% of protein
Raw tokenH_kinase_N:5:1.63e-36:135:132:139
2 HisKA_2#2
269-343 aa · 75 aa · 16.2% of protein
Raw tokenHisKA_2:269:2.52e-16:343:76:76
3 HATPase_c#3
363-460 aa · 98 aa · 21.2% of protein
Raw tokenHATPase_c:363:0.0000001:460:114:109
  • Raw architecture: H_kinase_N:5:1.63e-36:135:132:139#HisKA_2:269:2.52e-16:343:76:76#HATPase_c:363:0.0000001:460:114:109
  • Domain description: 1 H_kinase_N,1 HisKA_2,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_006408325::NZ_PZOR01000001.1::G00028
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2163220-2165196Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDA404_09855RefSeq proteinWP_330574846.1
Context group IDGCF_006408325::NZ_PZOR01000001.1::G00028
Context members
DA404_RS09850DA404_RS09855
Partner locus tags
DA404_RS09850DA404_RS09855
Partner old locus tags
DA404_09855DA404_09860
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_330574846.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDA404_RS09850Primary locus identifier stored in the genes table.
Old locus tagDA404_09855Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_PZOR01000001.1Sequence record reported by the local genomic context database.
Genomic interval2 163 220-2 164 608 nt1 389 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span2 163 220-2 165 196 ntGCF_006408325::NZ_PZOR01000001.1::G00028

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_006408325::NZ_PZOR01000001.1::G00028

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_PZOR01000001.1All displayed genes belong to this local TCS context.
Neighborhood span2 163 220-2 165 196 nt1 977 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 163 220 nt2 165 196 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DA404_RS09850GCF_006408325#DA404_RS09850
HKClassicCurrent focus

2 163 220-2 164 608 nt · Reverse (-)

Old locus DA404_09855RefSeq WP_330574846.1
DA404_RS09855GCF_006408325#DA404_RS09855
RRAmiR_NasR

2 164 621-2 165 196 nt · Reverse (-)

Old locus DA404_09860RefSeq WP_003423977.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1811307Run 6 · HK · 1 sequences
Representative sequenceGCF_006408325#DA404_RS09850The current gene is the representative for this cluster.
PFAM architectureGAF_PdtaS + HisKA_2 + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1811307

Simplified PFAM architecture for HKOC_1811307

PFAM domain coverage: 298 / 462 aa (64.5%)

1 aa462 aa
GAF_PdtaS: 3-134 aaGAF_PdtaSHisKA_2: 269-340 aaHisKA_2HATPase_c: 366-459 aaHATPase_c
GAF_PdtaSHisKA_2HATPase_c
  • Simplified architecture: GAF_PdtaS + HisKA_2 + HATPase_c
  • Raw architecture: GAF_PdtaS[3-134] | HisKA_2[269-340] | HATPase_c[366-459]
  • Domain count: 3
  • Matched identifier: HKOC_1811307
  • Positioned domains: GAF_PdtaS 3-134 ; HisKA_2 269-340 ; HATPase_c 366-459
Cluster members and taxonomy
Visualization

Representative gene: GCF_006408325#DA404_RS09850

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_006408325
AssemblyASM640832v1 · Contighaploid
Genome composition4 233 325 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 105 · HK 50 · RR 55CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key