1 HAMP#1
127-204 aa · 78 aa · 17.7% of protein
Raw token
HAMP:127:0.00000000667:204:78:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
DA402_RS19330
Histidine kinase, Classic
Clostridioides difficile · GCF_006408285
ClassHKTypeClassicLength440 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_006408285#DA402_RS19330Stable P2CS identifier used across views.
GenomeGCF_006408285Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length440 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage251 / 440 aa (57.0%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa440 aa
Domain-by-domain annotation3 items
2 HisKA#2
216-281 aa · 66 aa · 15.0% of protein
Raw token
HisKA:216:0.00000000165:281:66:643 HATPase_c#3
331-437 aa · 107 aa · 24.3% of protein
Raw token
HATPase_c:331:1.43e-26:437:107:109- Raw architecture: HAMP:127:0.00000000667:204:78:69#HisKA:216:0.00000000165:281:66:64#HATPase_c:331:1.43e-26:437:107:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_006408285::NZ_PZOO01000001.1::G00057
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span4136074-4138209Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDA402_19325RefSeq proteinWP_330363560.1
Context group ID
GCF_006408285::NZ_PZOO01000001.1::G00057Context members
DA402_RS19330DA402_RS19335
Partner locus tags
DA402_RS19330DA402_RS19335
Partner old locus tags
DA402_19325DA402_19330
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_330363560.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagDA402_RS19330Primary locus identifier stored in the genes table.
Old locus tagDA402_19325Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_PZOO01000001.1Sequence record reported by the local genomic context database.
Genomic interval4 136 074-4 137 396 nt1 323 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span4 136 074-4 138 209 ntGCF_006408285::NZ_PZOO01000001.1::G00057
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_006408285::NZ_PZOO01000001.1::G00057Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_PZOO01000001.1All displayed genes belong to this local TCS context.
Neighborhood span4 136 074-4 138 209 nt2 136 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
4 136 074 nt4 138 209 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
DA402_RS19330GCF_006408285#DA402_RS19330
HKClassicCurrent focus
4 136 074-4 137 396 nt · Reverse (-)
DA402_RS19335GCF_006408285#DA402_RS19335
RROmpR
4 137 517-4 138 209 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000451185#QQ3_RS02805Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2072080
Simplified PFAM architecture for HKOC_2072080
PFAM domain coverage: 223 / 440 aa (50.7%)
1 aa440 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[154-204] | HisKA[217-281] | HATPase_c[331-437]
- Domain count: 3
- Matched identifier: HKOC_2072080
- Positioned domains: HAMP 154-204 ; HisKA 217-281 ; HATPase_c 331-437
Cluster members and taxonomy
Representative gene: GCF_000451185#QQ3_RS02805
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_006408285
AssemblyASM640828v1 · Contighaploid
Genome composition4 221 541 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 102 · HK 49 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key