1 HisKA#1
195-255 aa · 61 aa · 14.8% of protein
Raw token
HisKA:195:0.000000000000186:255:61:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
DA402_RS01315
Histidine kinase, Classic
Clostridioides difficile · GCF_006408285
ClassHKTypeClassicLength413 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_006408285#DA402_RS01315Stable P2CS identifier used across views.
GenomeGCF_006408285Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length413 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage167 / 413 aa (40.4%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Domain-by-domain annotation2 items
2 HATPase_c#2
302-407 aa · 106 aa · 25.7% of protein
Raw token
HATPase_c:302:1.45e-25:407:106:109- Raw architecture: HisKA:195:0.000000000000186:255:61:64#HATPase_c:302:1.45e-25:407:106:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_006408285::NZ_PZOO01000001.1::G00003
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span266306-268244Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDA402_01315RefSeq proteinWP_003434453.1
Context group ID
GCF_006408285::NZ_PZOO01000001.1::G00003Context members
DA402_RS01315DA402_RS01320
Partner locus tags
DA402_RS01315DA402_RS01320
Partner old locus tags
DA402_01315DA402_01320
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003434453.1Primary protein accession used for annex mappings.
UniProt accessionA0A6N3HS12Primary UniProt accession resolved in the annex database.
UniProt IDA0A6N3HS12_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagDA402_RS01315Primary locus identifier stored in the genes table.
Old locus tagDA402_01315Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_PZOO01000001.1Sequence record reported by the local genomic context database.
Genomic interval266 306-267 547 nt1 242 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span266 306-268 244 ntGCF_006408285::NZ_PZOO01000001.1::G00003
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_006408285::NZ_PZOO01000001.1::G00003Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_PZOO01000001.1All displayed genes belong to this local TCS context.
Neighborhood span266 306-268 244 nt1 939 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
266 306 nt268 244 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
DA402_RS01315GCF_006408285#DA402_RS01315
HKClassicCurrent focus
266 306-267 547 nt · Reverse (-)
DA402_RS01320GCF_006408285#DA402_RS01320
RROmpR
267 558-268 244 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000235905#HMPREF9945_RS15735Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2328176
Simplified PFAM architecture for HKOC_2328176
PFAM domain coverage: 172 / 413 aa (41.6%)
1 aa413 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[193-255] | HATPase_c[302-410]
- Domain count: 2
- Matched identifier: HKOC_2328176
- Positioned domains: HisKA 193-255 ; HATPase_c 302-410
Cluster members and taxonomy
Representative gene: GCF_000235905#HMPREF9945_RS15735
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_006408285
AssemblyASM640828v1 · Contighaploid
Genome composition4 221 541 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 102 · HK 49 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key