1 HisKA#1
558-624 aa · 67 aa · 8.6% of protein
Raw token
HisKA:558:1.43e-18:624:67:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
DA431_RS13725
Histidine kinase, Classic
Clostridioides difficile · GCF_006381075
ClassHKTypeClassicLength778 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_006381075#DA431_RS13725Stable P2CS identifier used across views.
GenomeGCF_006381075Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length778 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage172 / 778 aa (22.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Domain-by-domain annotation2 items
2 HATPase_c#2
671-775 aa · 105 aa · 13.5% of protein
Raw token
HATPase_c:671:0.000000000455:775:110:109- Raw architecture: HisKA:558:1.43e-18:624:67:64#HATPase_c:671:0.000000000455:775:110:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_006381075::NZ_PZRK01000001.1::G00040
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2875897-2878921Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDA431_13705RefSeq proteinWP_021394881.1
Context group ID
GCF_006381075::NZ_PZRK01000001.1::G00040Context members
DA431_RS13725DA431_RS13730
Partner locus tags
DA431_RS13725DA431_RS13730
Partner old locus tags
DA431_13705DA431_13710
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_021394881.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagDA431_RS13725Primary locus identifier stored in the genes table.
Old locus tagDA431_13705Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_PZRK01000001.1Sequence record reported by the local genomic context database.
Genomic interval2 875 897-2 878 233 nt2 337 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span2 875 897-2 878 921 ntGCF_006381075::NZ_PZRK01000001.1::G00040
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_006381075::NZ_PZRK01000001.1::G00040Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_PZRK01000001.1All displayed genes belong to this local TCS context.
Neighborhood span2 875 897-2 878 921 nt3 025 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 875 897 nt2 878 921 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
DA431_RS13725GCF_006381075#DA431_RS13725
HKClassicCurrent focus
2 875 897-2 878 233 nt · Reverse (-)
DA431_RS13730GCF_006381075#DA431_RS13730
RROmpR
2 878 205-2 878 921 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000449025#QCG_RS13670Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0599073
Simplified PFAM architecture for HKOC_0599073
PFAM domain coverage: 172 / 778 aa (22.1%)
1 aa778 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[558-624] | HATPase_c[671-775]
- Domain count: 2
- Matched identifier: HKOC_0599073
- Positioned domains: HisKA 558-624 ; HATPase_c 671-775
Cluster members and taxonomy
Representative gene: GCF_000449025#QCG_RS13670
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_006381075
AssemblyASM638107v1 · Contighaploid
Genome composition4 498 460 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 100 · HK 47 · RR 52CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key