Gene detail

DA427_RS09515

Histidine kinase, Classic

Clostridioides difficile · GCF_006381025

ClassHKTypeClassicLength425 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_006381025#DA427_RS09515Stable P2CS identifier used across views.
GenomeGCF_006381025Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2215984Run 6 · 335 sequences · id 100% · cov 80%
External referencesWP_009890242.1 · A0A0H3N4E5 · MIST4 DA427_RS09515RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length425 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage183 / 425 aa (43.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa425 aa
HisKA: 196-260 aa (65 aa)1HATPase_c: 307-424 aa (118 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
196-260 aa · 65 aa · 15.3% of protein
Raw tokenHisKA:196:0.0000000000151:260:65:64
2 HATPase_c#2
307-424 aa · 118 aa · 27.8% of protein
Raw tokenHATPase_c:307:2.03e-18:424:119:109
  • Raw architecture: HisKA:196:0.0000000000151:260:65:64#HATPase_c:307:2.03e-18:424:119:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_006381025::NZ_PZRH01000001.1::G00025
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2043328-2045257Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDA427_09515RefSeq proteinWP_009890242.1
Context group IDGCF_006381025::NZ_PZRH01000001.1::G00025
Context members
DA427_RS09510DA427_RS09515
Partner locus tags
DA427_RS09510DA427_RS09515
Partner old locus tags
DA427_09510DA427_09515
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009890242.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3N4E5Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3N4E5_CLODCDisplay identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDA427_RS09515Primary locus identifier stored in the genes table.
Old locus tagDA427_09515Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_PZRH01000001.1Sequence record reported by the local genomic context database.
Genomic interval2 043 980-2 045 257 nt1 278 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span2 043 328-2 045 257 ntGCF_006381025::NZ_PZRH01000001.1::G00025

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_006381025::NZ_PZRH01000001.1::G00025

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_PZRH01000001.1All displayed genes belong to this local TCS context.
Neighborhood span2 043 328-2 045 257 nt1 930 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 043 328 nt2 045 257 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DA427_RS09510GCF_006381025#DA427_RS09510
RROmpR

2 043 328-2 043 996 nt · Forward (+)

Old locus DA427_09510RefSeq WP_003424455.1
DA427_RS09515GCF_006381025#DA427_RS09515
HKClassicCurrent focus

2 043 980-2 045 257 nt · Forward (+)

Old locus DA427_09515RefSeq WP_009890242.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2215984Run 6 · HK · 335 sequences
Representative sequenceGCF_000003215#QAC_RS0210660Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2215984

Simplified PFAM architecture for HKOC_2215984

PFAM domain coverage: 179 / 425 aa (42.1%)

1 aa425 aa
HisKA: 197-260 aaHisKAHATPase_c: 308-422 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[197-260] | HATPase_c[308-422]
  • Domain count: 2
  • Matched identifier: HKOC_2215984
  • Positioned domains: HisKA 197-260 ; HATPase_c 308-422
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0210660

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 335 total members. Page 1 / 7.

GCF_000003215#QAC_RS0210660 (representative)
QAC_RS0210660 · HK · Classic
RefSeq: WP_009890242.1
UniProt: A0A0H3N4E5
GCF_000027105#CDR20291_RS11070
CDR20291_RS11070 · HK · Classic
RefSeq: WP_009890242.1
UniProt: A0A0H3N4E5
GCF_000085225#CD196_RS10760
CD196_RS10760 · HK · Classic
RefSeq: WP_009890242.1
UniProt: A0A0H3N4E5
GCF_000154645#UAA_RS0212535
UAA_RS0212535 · HK · Classic
RefSeq: WP_009890242.1
UniProt: A0A0H3N4E5
GCF_000154665#QAD_RS0210825
QAD_RS0210825 · HK · Classic
RefSeq: WP_009890242.1
UniProt: A0A0H3N4E5
GCF_000154685#AEC_RS0212145
AEC_RS0212145 · HK · Classic
RefSeq: WP_009890242.1
UniProt: A0A0H3N4E5
GCF_000155045#EAA_RS0210565
EAA_RS0210565 · HK · Classic
RefSeq: WP_009890242.1
UniProt: A0A0H3N4E5
GCF_000210455#CD7855_RS10575
CD7855_RS10575 · HK · Classic
RefSeq: WP_009890242.1
UniProt: A0A0H3N4E5
GCF_000211235#CDBI1_RS10670
CDBI1_RS10670 · HK · Classic
RefSeq: WP_009890242.1
UniProt: A0A0H3N4E5
GCF_000451785#QSO_RS09400
QSO_RS09400 · HK · Classic
RefSeq: WP_009890242.1
UniProt: A0A0H3N4E5
GCF_000451885#QU5_RS10475
QU5_RS10475 · HK · Classic
RefSeq: WP_009890242.1
UniProt: A0A0H3N4E5
GCF_001484885#CD26A54R_RS10580
CD26A54R_RS10580 · HK · Classic
RefSeq: WP_009890242.1
UniProt: A0A0H3N4E5
GCF_001484895#CD26A54S_RS10695
CD26A54S_RS10695 · HK · Classic
RefSeq: WP_009890242.1
UniProt: A0A0H3N4E5
GCF_001857645#HMPREF3082_RS02060
HMPREF3082_RS02060 · HK · Classic
RefSeq: WP_009890242.1
UniProt: A0A0H3N4E5
GCF_001971835#BER28_RS11025
BER28_RS11025 · HK · Classic
RefSeq: WP_009890242.1
UniProt: A0A0H3N4E5
GCF_001972015#BER29_RS10970
BER29_RS10970 · HK · Classic
RefSeq: WP_009890242.1
UniProt: A0A0H3N4E5
GCF_002301945#BGU80_RS02735
BGU80_RS02735 · HK · Classic
RefSeq: WP_009890242.1
UniProt: A0A0H3N4E5
GCF_002302765#BGV01_RS03110
BGV01_RS03110 · HK · Classic
RefSeq: WP_009890242.1
UniProt: A0A0H3N4E5
GCF_002302845#BGV07_RS04835
BGV07_RS04835 · HK · Classic
RefSeq: WP_009890242.1
UniProt: A0A0H3N4E5
GCF_002303165#BGV24_RS14510
BGV24_RS14510 · HK · Classic
RefSeq: WP_009890242.1
UniProt: A0A0H3N4E5
GCF_002335485#NCKUH21_RS10435
NCKUH21_RS10435 · HK · Classic
RefSeq: WP_009890242.1
UniProt: A0A0H3N4E5
GCF_002812585#CWR57_RS10395
CWR57_RS10395 · HK · Classic
RefSeq: WP_009890242.1
UniProt: A0A0H3N4E5
GCF_002945415#C3W74_RS11070
C3W74_RS11070 · HK · Classic
RefSeq: WP_009890242.1
UniProt: A0A0H3N4E5
GCF_002945515#C3L34_RS11555
C3L34_RS11555 · HK · Classic
RefSeq: WP_009890242.1
UniProt: A0A0H3N4E5
GCF_002945665#C3347_RS11070
C3347_RS11070 · HK · Classic
RefSeq: WP_009890242.1
UniProt: A0A0H3N4E5
GCF_002945755#C3348_RS11075
C3348_RS11075 · HK · Classic
RefSeq: WP_009890242.1
UniProt: A0A0H3N4E5
GCF_002945855#C3350_RS11085
C3350_RS11085 · HK · Classic
RefSeq: WP_009890242.1
UniProt: A0A0H3N4E5
GCF_002945945#C3349_RS11075
C3349_RS11075 · HK · Classic
RefSeq: WP_009890242.1
UniProt: A0A0H3N4E5
GCF_002946035#C3351_RS11080
C3351_RS11080 · HK · Classic
RefSeq: WP_009890242.1
UniProt: A0A0H3N4E5
GCF_002946135#C3352_RS11080
C3352_RS11080 · HK · Classic
RefSeq: WP_009890242.1
UniProt: A0A0H3N4E5
GCF_002946195#C3353_RS11070
C3353_RS11070 · HK · Classic
RefSeq: WP_009890242.1
UniProt: A0A0H3N4E5
GCF_002954285#AMR92_RS00655
AMR92_RS00655 · HK · Classic
RefSeq: WP_009890242.1
UniProt: A0A0H3N4E5
GCF_003313545#CDIF27638_RS11080
CDIF27638_RS11080 · HK · Classic
RefSeq: WP_009890242.1
UniProt: A0A0H3N4E5
GCF_003313585#CDIF27640_RS11070
CDIF27640_RS11070 · HK · Classic
RefSeq: WP_009890242.1
UniProt: A0A0H3N4E5
GCF_003482035#CDIF28196_RS11085
CDIF28196_RS11085 · HK · Classic
RefSeq: WP_009890242.1
UniProt: A0A0H3N4E5
GCF_003597795#DA426_RS08840
DA426_RS08840 · HK · Classic
RefSeq: WP_009890242.1
UniProt: A0A0H3N4E5
GCF_003597815#DA430_RS11075
DA430_RS11075 · HK · Classic
RefSeq: WP_009890242.1
UniProt: A0A0H3N4E5
GCF_003597835#DA432_RS11030
DA432_RS11030 · HK · Classic
RefSeq: WP_009890242.1
UniProt: A0A0H3N4E5
GCF_003597895#DA422_RS10840
DA422_RS10840 · HK · Classic
RefSeq: WP_009890242.1
UniProt: A0A0H3N4E5
GCF_003597915#DA436_RS11025
DA436_RS11025 · HK · Classic
RefSeq: WP_009890242.1
UniProt: A0A0H3N4E5
GCF_003625415#C0215_RS01030
C0215_RS01030 · HK · Classic
RefSeq: WP_009890242.1
UniProt: A0A0H3N4E5
GCF_003625425#C0983_RS03565
C0983_RS03565 · HK · Classic
RefSeq: WP_009890242.1
UniProt: A0A0H3N4E5
GCF_003625435#C0984_RS02760
C0984_RS02760 · HK · Classic
RefSeq: WP_009890242.1
UniProt: A0A0H3N4E5
GCF_003862685#EGM06_RS03375
EGM06_RS03375 · HK · Classic
RefSeq: WP_009890242.1
UniProt: A0A0H3N4E5
GCF_003863035#EGL82_RS04405
EGL82_RS04405 · HK · Classic
RefSeq: WP_009890242.1
UniProt: A0A0H3N4E5
GCF_003863055#EGM11_RS00940
EGM11_RS00940 · HK · Classic
RefSeq: WP_009890242.1
UniProt: A0A0H3N4E5
GCF_003863075#EGL79_RS04640
EGL79_RS04640 · HK · Classic
RefSeq: WP_009890242.1
UniProt: A0A0H3N4E5
GCF_003863145#EGM12_RS00940
EGM12_RS00940 · HK · Classic
RefSeq: WP_009890242.1
UniProt: A0A0H3N4E5
GCF_003863195#EGM01_RS03045
EGM01_RS03045 · HK · Classic
RefSeq: WP_009890242.1
UniProt: A0A0H3N4E5
GCF_003863275#EGL83_RS00940
EGL83_RS00940 · HK · Classic
RefSeq: WP_009890242.1
UniProt: A0A0H3N4E5

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_006381025
AssemblyASM638102v1 · Contighaploid
Genome composition4 204 496 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 106 · HK 50 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key