1 HisKA#1
558-624 aa · 67 aa · 8.6% of protein
Raw token
HisKA:558:1.46e-18:624:67:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
DA427_RS07225
Histidine kinase, Classic
Clostridioides difficile · GCF_006381025
ClassHKTypeClassicLength778 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_006381025#DA427_RS07225Stable P2CS identifier used across views.
GenomeGCF_006381025Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length778 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage172 / 778 aa (22.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa778 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
671-775 aa · 105 aa · 13.5% of protein
Raw token
HATPase_c:671:0.000000000415:775:110:109- Raw architecture: HisKA:558:1.46e-18:624:67:64#HATPase_c:671:0.000000000415:775:110:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_006381025::NZ_PZRH01000001.1::G00020
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1524603-1527627Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDA427_07215RefSeq proteinWP_012816303.1
Context group ID
GCF_006381025::NZ_PZRH01000001.1::G00020Context members
DA427_RS07220DA427_RS07225
Partner locus tags
DA427_RS07220DA427_RS07225
Partner old locus tags
DA427_07210DA427_07215
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_012816303.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3N5Q0Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3N5Q0_CLODCDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
Reference hubs
GO terms
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagDA427_RS07225Primary locus identifier stored in the genes table.
Old locus tagDA427_07215Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_PZRH01000001.1Sequence record reported by the local genomic context database.
Genomic interval1 525 291-1 527 627 nt2 337 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1 524 603-1 527 627 ntGCF_006381025::NZ_PZRH01000001.1::G00020
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_006381025::NZ_PZRH01000001.1::G00020Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_PZRH01000001.1All displayed genes belong to this local TCS context.
Neighborhood span1 524 603-1 527 627 nt3 025 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 524 603 nt1 527 627 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
DA427_RS07220GCF_006381025#DA427_RS07220
RROmpR
1 524 603-1 525 319 nt · Forward (+)
DA427_RS07225GCF_006381025#DA427_RS07225
HKClassicCurrent focus
1 525 291-1 527 627 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000003215#QAC_RS0212970Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0598797
Simplified PFAM architecture for HKOC_0598797
PFAM domain coverage: 172 / 778 aa (22.1%)
1 aa778 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[558-624] | HATPase_c[671-775]
- Domain count: 2
- Matched identifier: HKOC_0598797
- Positioned domains: HisKA 558-624 ; HATPase_c 671-775
Cluster members and taxonomy
Representative gene: GCF_000003215#QAC_RS0212970
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_006381025
AssemblyASM638102v1 · Contighaploid
Genome composition4 204 496 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 106 · HK 50 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key