Gene detail

DA427_RS05335

Histidine kinase, Classic

Clostridioides difficile · GCF_006381025

ClassHKTypeClassicLength306 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_006381025#DA427_RS05335Stable P2CS identifier used across views.
GenomeGCF_006381025Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2881356Run 6 · 16 sequences · id 100% · cov 80%
External referencesWP_021419409.1 · MIST4 DA427_RS05335RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length306 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage157 / 306 aa (51.3%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa306 aa
HisKA: 95-142 aa (48 aa)1HATPase_c: 188-296 aa (109 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
95-142 aa · 48 aa · 15.7% of protein
Raw tokenHisKA:95:0.00000112:142:53:64
2 HATPase_c#2
188-296 aa · 109 aa · 35.6% of protein
Raw tokenHATPase_c:188:4.59e-23:296:109:109
  • Raw architecture: HisKA:95:0.00000112:142:53:64#HATPase_c:188:4.59e-23:296:109:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_006381025::NZ_PZRH01000001.1::G00013
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1065927-1067633Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDA427_05325RefSeq proteinWP_021419409.1
Context group IDGCF_006381025::NZ_PZRH01000001.1::G00013
Context members
DA427_RS05330DA427_RS05335
Partner locus tags
DA427_RS05330DA427_RS05335
Partner old locus tags
DA427_05320DA427_05325
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021419409.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDA427_RS05335Primary locus identifier stored in the genes table.
Old locus tagDA427_05325Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_PZRH01000001.1Sequence record reported by the local genomic context database.
Genomic interval1 066 713-1 067 633 nt921 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1 065 927-1 067 633 ntGCF_006381025::NZ_PZRH01000001.1::G00013

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_006381025::NZ_PZRH01000001.1::G00013

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_PZRH01000001.1All displayed genes belong to this local TCS context.
Neighborhood span1 065 927-1 067 633 nt1 707 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 065 927 nt1 067 633 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DA427_RS05330GCF_006381025#DA427_RS05330
RROmpR

1 065 927-1 066 619 nt · Forward (+)

Old locus DA427_05320RefSeq WP_003429090.1
DA427_RS05335GCF_006381025#DA427_RS05335
HKClassicCurrent focus

1 066 713-1 067 633 nt · Forward (+)

Old locus DA427_05325RefSeq WP_021419409.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2881356Run 6 · HK · 16 sequences
Representative sequenceGCF_001484885#CD26A54R_RS14740Use this link to inspect the representative gene detail.
PFAM architectureHATPase_c1 domain in the representative PFAM annotation.

PFAM architecture for HKOC_2881356

Simplified PFAM architecture for HKOC_2881356

PFAM domain coverage: 109 / 306 aa (35.6%)

1 aa306 aa
HATPase_c: 189-297 aaHATPase_c
HATPase_c
  • Simplified architecture: HATPase_c
  • Raw architecture: HATPase_c[189-297]
  • Domain count: 1
  • Matched identifier: HKOC_2881356
  • Positioned domains: HATPase_c 189-297
Cluster members and taxonomy
Visualization

Representative gene: GCF_001484885#CD26A54R_RS14740

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_006381025
AssemblyASM638102v1 · Contighaploid
Genome composition4 204 496 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 106 · HK 50 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key