1 HisKA#1
449-514 aa · 66 aa · 9.8% of protein
Raw token
HisKA:449:0.00000000352:514:66:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
DA428_RS03015
Histidine kinase, Classic
Clostridioides difficile · GCF_006381005
ClassHKTypeClassicLength671 aaTM0ValidatedNoCompleteYesContexttriad
Gene IDGCF_006381005#DA428_RS03015Stable P2CS identifier used across views.
GenomeGCF_006381005Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length671 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage170 / 671 aa (25.3%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa671 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
565-668 aa · 104 aa · 15.5% of protein
Raw token
HATPase_c:565:4.04e-30:668:104:109- Raw architecture: HisKA:449:0.00000000352:514:66:64#HATPase_c:565:4.04e-30:668:104:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labeltriadGCF_006381005::NZ_PZRI01000001.1::G00005
Group size33 locus tags listed below.
HK / RR1 / 2Counts resolved for the local TCS neighborhood.
Context span580364-583858Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDA428_03020RefSeq proteinWP_021364827.1
Context group ID
GCF_006381005::NZ_PZRI01000001.1::G00005Context members
DA428_RS03010DA428_RS03015DA428_RS03020
Partner locus tags
DA428_RS03010DA428_RS03015DA428_RS03020
Partner old locus tags
DA428_03015DA428_03020DA428_03025
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_021364827.1Primary protein accession used for annex mappings.
UniProt accessionA0AAN6A5L1Primary UniProt accession resolved in the annex database.
UniProt IDA0AAN6A5L1_CLODIDisplay identifier provided by UniProt.
GO / PubMed5 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagDA428_RS03015Primary locus identifier stored in the genes table.
Old locus tagDA428_03020Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_PZRI01000001.1Sequence record reported by the local genomic context database.
Genomic interval581 113-583 128 nt2 016 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span580 364-583 858 ntGCF_006381005::NZ_PZRI01000001.1::G00005
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_006381005::NZ_PZRI01000001.1::G00005Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labeltriadNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_PZRI01000001.1All displayed genes belong to this local TCS context.
Neighborhood span580 364-583 858 nt3 495 nt
Members31 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
580 364 nt583 858 nt
Neighborhood gene cards
3 genes in the current local neighborhood.
DA428_RS03010GCF_006381005#DA428_RS03010
RROmpR
580 364-581 041 nt · Forward (+)
DA428_RS03015GCF_006381005#DA428_RS03015
HKClassicCurrent focus
581 113-583 128 nt · Forward (+)
DA428_RS03020GCF_006381005#DA428_RS03020
RROmpR
583 178-583 858 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000448745#QC1_RS16905Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0842594
Simplified PFAM architecture for HKOC_0842594
PFAM domain coverage: 170 / 671 aa (25.3%)
1 aa671 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[450-514] | HATPase_c[563-667]
- Domain count: 2
- Matched identifier: HKOC_0842594
- Positioned domains: HisKA 450-514 ; HATPase_c 563-667
Cluster members and taxonomy
Representative gene: GCF_000448745#QC1_RS16905
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_006381005
AssemblyASM638100v1 · Contighaploid
Genome composition4 292 951 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 98 · HK 46 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key