1 HisKA#1
457-524 aa · 68 aa · 9.9% of protein
Raw token
HisKA:457:0.0000000000000227:524:68:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
DA425_RS12410
Histidine kinase, Classic
Clostridioides difficile · GCF_006380995
ClassHKTypeClassicLength686 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_006380995#DA425_RS12410Stable P2CS identifier used across views.
GenomeGCF_006380995Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length686 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage162 / 686 aa (23.6%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa686 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
570-663 aa · 94 aa · 13.7% of protein
Raw token
HATPase_c:570:0.00000000000188:663:98:109- Raw architecture: HisKA:457:0.0000000000000227:524:68:64#HATPase_c:570:0.00000000000188:663:98:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_006380995::NZ_PZRG01000004.1::G00038
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2456197-2459145Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDA425_12420RefSeq proteinWP_172617897.1
Context group ID
GCF_006380995::NZ_PZRG01000004.1::G00038Context members
DA425_RS12410DA425_RS12420
Partner locus tags
DA425_RS12410DA425_RS12420
Partner old locus tags
DA425_12420DA425_12430
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_172617897.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagDA425_RS12410Primary locus identifier stored in the genes table.
Old locus tagDA425_12420Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_PZRG01000004.1Sequence record reported by the local genomic context database.
Genomic interval2 456 197-2 458 257 nt2 061 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span2 456 197-2 459 145 ntGCF_006380995::NZ_PZRG01000004.1::G00038
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_006380995::NZ_PZRG01000004.1::G00038Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_PZRG01000004.1All displayed genes belong to this local TCS context.
Neighborhood span2 456 197-2 459 145 nt2 949 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 456 197 nt2 459 145 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
DA425_RS12410GCF_006380995#DA425_RS12410
HKClassicCurrent focus
2 456 197-2 458 257 nt · Reverse (-)
DA425_RS12420GCF_006380995#DA425_RS12420
RROmpR
2 458 453-2 459 145 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_003862935#EGL90_RS04285Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0801575
Simplified PFAM architecture for HKOC_0801575
PFAM domain coverage: 160 / 686 aa (23.3%)
1 aa686 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[457-524] | HATPase_c[571-662]
- Domain count: 2
- Matched identifier: HKOC_0801575
- Positioned domains: HisKA 457-524 ; HATPase_c 571-662
Cluster members and taxonomy
Representative gene: GCF_003862935#EGL90_RS04285
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_006380995
AssemblyASM638099v1 · Contighaploid
Genome composition4 167 354 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 101 · HK 48 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key