1 HisKA#1
245-309 aa · 65 aa · 13.9% of protein
Raw token
HisKA:245:0.000000000002:309:65:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
DA425_RS04360
Histidine kinase, Classic
Clostridioides difficile · GCF_006380995
ClassHKTypeClassicLength468 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_006380995#DA425_RS04360Stable P2CS identifier used across views.
GenomeGCF_006380995Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length468 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage175 / 468 aa (37.4%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa468 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
357-466 aa · 110 aa · 23.5% of protein
Raw token
HATPase_c:357:9.67e-18:466:110:109- Raw architecture: HisKA:245:0.000000000002:309:65:64#HATPase_c:357:9.67e-18:466:110:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_006380995::NZ_PZRG01000004.1::G00013
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span714016-716174Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDA425_04380RefSeq proteinWP_124962661.1
Context group ID
GCF_006380995::NZ_PZRG01000004.1::G00013Context members
DA425_RS04355DA425_RS04360
Partner locus tags
DA425_RS04355DA425_RS04360
Partner old locus tags
DA425_04375DA425_04380
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_124962661.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagDA425_RS04360Primary locus identifier stored in the genes table.
Old locus tagDA425_04380Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_PZRG01000004.1Sequence record reported by the local genomic context database.
Genomic interval714 768-716 174 nt1 407 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span714 016-716 174 ntGCF_006380995::NZ_PZRG01000004.1::G00013
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_006380995::NZ_PZRG01000004.1::G00013Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_PZRG01000004.1All displayed genes belong to this local TCS context.
Neighborhood span714 016-716 174 nt2 159 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
714 016 nt716 174 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
DA425_RS04355GCF_006380995#DA425_RS04355
RROmpR
714 016-714 723 nt · Forward (+)
DA425_RS04360GCF_006380995#DA425_RS04360
HKClassicCurrent focus
714 768-716 174 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_003862935#EGL90_RS07295Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1740356
Simplified PFAM architecture for HKOC_1740356
PFAM domain coverage: 175 / 468 aa (37.4%)
1 aa468 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[245-310] | HATPase_c[358-466]
- Domain count: 2
- Matched identifier: HKOC_1740356
- Positioned domains: HisKA 245-310 ; HATPase_c 358-466
Cluster members and taxonomy
Representative gene: GCF_003862935#EGL90_RS07295
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_006380995
AssemblyASM638099v1 · Contighaploid
Genome composition4 167 354 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 101 · HK 48 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key