1 HAMP#1
127-204 aa · 78 aa · 17.7% of protein
Raw token
HAMP:127:0.00000000442:204:78:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
DA423_RS03515
Histidine kinase, Classic
Clostridioides difficile · GCF_006380955
ClassHKTypeClassicLength440 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_006380955#DA423_RS03515Stable P2CS identifier used across views.
GenomeGCF_006380955Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length440 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage251 / 440 aa (57.0%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa440 aa
Domain-by-domain annotation3 items
2 HisKA#2
216-281 aa · 66 aa · 15.0% of protein
Raw token
HisKA:216:0.00000000346:281:66:643 HATPase_c#3
331-437 aa · 107 aa · 24.3% of protein
Raw token
HATPase_c:331:4e-26:437:107:109- Raw architecture: HAMP:127:0.00000000442:204:78:69#HisKA:216:0.00000000346:281:66:64#HATPase_c:331:4e-26:437:107:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_006380955::NZ_PZRE01000002.1::G00005
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span510137-512272Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDA423_03515RefSeq proteinWP_330382310.1
Context group ID
GCF_006380955::NZ_PZRE01000002.1::G00005Context members
DA423_RS03510DA423_RS03515
Partner locus tags
DA423_RS03510DA423_RS03515
Partner old locus tags
DA423_03510DA423_03515
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_330382310.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagDA423_RS03515Primary locus identifier stored in the genes table.
Old locus tagDA423_03515Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_PZRE01000002.1Sequence record reported by the local genomic context database.
Genomic interval510 950-512 272 nt1 323 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span510 137-512 272 ntGCF_006380955::NZ_PZRE01000002.1::G00005
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_006380955::NZ_PZRE01000002.1::G00005Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_PZRE01000002.1All displayed genes belong to this local TCS context.
Neighborhood span510 137-512 272 nt2 136 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
510 137 nt512 272 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
DA423_RS03510GCF_006380955#DA423_RS03510
RROmpR
510 137-510 829 nt · Forward (+)
DA423_RS03515GCF_006380955#DA423_RS03515
HKClassicCurrent focus
510 950-512 272 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000451305#QEE_RS02815Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2072081
Simplified PFAM architecture for HKOC_2072081
PFAM domain coverage: 223 / 440 aa (50.7%)
1 aa440 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[154-204] | HisKA[217-281] | HATPase_c[331-437]
- Domain count: 3
- Matched identifier: HKOC_2072081
- Positioned domains: HAMP 154-204 ; HisKA 217-281 ; HATPase_c 331-437
Cluster members and taxonomy
Representative gene: GCF_000451305#QEE_RS02815
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_006380955
AssemblyASM638095v1 · Contighaploid
Genome composition4 451 150 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 100 · HK 47 · RR 52CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key