Gene detail

DA417_RS12880

Histidine kinase, Classic

Clostridioides difficile · GCF_006380895

ClassHKTypeClassicLength370 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_006380895#DA417_RS12880Stable P2CS identifier used across views.
GenomeGCF_006380895Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2684604Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_180920258.1 · MIST4 DA417_RS12880RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length370 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage161 / 370 aa (43.5%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for DA417_RS12880
Domain-by-domain annotation2 items
1 HisKA#1
145-208 aa · 64 aa · 17.3% of protein
Raw tokenHisKA:145:0.000000000000415:208:64:64
2 HATPase_c#2
258-354 aa · 97 aa · 26.2% of protein
Raw tokenHATPase_c:258:1.73e-21:354:97:109
  • Raw architecture: HisKA:145:0.000000000000415:208:64:64#HATPase_c:258:1.73e-21:354:97:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_006380895::NZ_PZRA01000009.1::G00011
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span561565-563428Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDA417_12880RefSeq proteinWP_180920258.1
Context group IDGCF_006380895::NZ_PZRA01000009.1::G00011
Context members
DA417_RS12880DA417_RS12885
Partner locus tags
DA417_RS12880DA417_RS12885
Partner old locus tags
DA417_12880DA417_12885
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_180920258.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDA417_RS12880Primary locus identifier stored in the genes table.
Old locus tagDA417_12880Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_PZRA01000009.1Sequence record reported by the local genomic context database.
Genomic interval561 565-562 677 nt1 113 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span561 565-563 428 ntGCF_006380895::NZ_PZRA01000009.1::G00011

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_006380895::NZ_PZRA01000009.1::G00011

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_PZRA01000009.1All displayed genes belong to this local TCS context.
Neighborhood span561 565-563 428 nt1 864 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
561 565 nt563 428 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DA417_RS12880GCF_006380895#DA417_RS12880
HKClassicCurrent focus

561 565-562 677 nt · Reverse (-)

Old locus DA417_12880RefSeq WP_180920258.1
DA417_RS12885GCF_006380895#DA417_RS12885
RROmpR

562 727-563 428 nt · Reverse (-)

Old locus DA417_12885RefSeq WP_009889529.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2684604Run 6 · HK · 1 sequences
Representative sequenceGCF_006380895#DA417_RS12880The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2684604

Simplified PFAM architecture for HKOC_2684604

PFAM domain coverage: 161 / 370 aa (43.5%)

1 aa370 aa
HisKA: 146-208 aaHisKAHATPase_c: 258-355 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[146-208] | HATPase_c[258-355]
  • Domain count: 2
  • Matched identifier: HKOC_2684604
  • Positioned domains: HisKA 146-208 ; HATPase_c 258-355
Cluster members and taxonomy
Visualization

Representative gene: GCF_006380895#DA417_RS12880

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_006380895
AssemblyASM638089v1 · Contighaploid
Genome composition4 192 092 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 106 · HK 50 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key