Gene detail

DA416_RS09375

Histidine kinase, Classic

Clostridioides difficile · GCF_006380835

ClassHKTypeClassicLength664 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_006380835#DA416_RS09375Stable P2CS identifier used across views.
GenomeGCF_006380835Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0860374Run 6 · 25 sequences · id 100% · cov 80%
External referencesWP_021411151.1 · MIST4 DA416_RS09375RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

SBP_bac_3HisKAHATPase_c
Protein length664 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage386 / 664 aa (58.1%)Merged over positioned domains only.
Domain description1 SBP_bac_3,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa664 aa
SBP_bac_3: 58-278 aa (221 aa)1HisKA: 446-508 aa (63 aa)2HATPase_c: 557-658 aa (102 aa)3
Domain-by-domain annotation3 items
1 SBP_bac_3#1
58-278 aa · 221 aa · 33.3% of protein
Raw tokenSBP_bac_3:58:1.67e-41:278:230:224
2 HisKA#2
446-508 aa · 63 aa · 9.5% of protein
Raw tokenHisKA:446:0.0000000000000424:508:63:64
3 HATPase_c#3
557-658 aa · 102 aa · 15.4% of protein
Raw tokenHATPase_c:557:1.72e-23:658:103:109
  • Raw architecture: SBP_bac_3:58:1.67e-41:278:230:224#HisKA:446:0.0000000000000424:508:63:64#HATPase_c:557:1.72e-23:658:103:109
  • Domain description: 1 SBP_bac_3,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_006380835::NZ_PZQZ01000003.1::G00028
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1939386-1942702Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDA416_09385RefSeq proteinWP_021411151.1
Context group IDGCF_006380835::NZ_PZQZ01000003.1::G00028
Context members
DA416_RS09375DA416_RS09380
Partner locus tags
DA416_RS09375DA416_RS09380
Partner old locus tags
DA416_09385DA416_09390
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021411151.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDA416_RS09375Primary locus identifier stored in the genes table.
Old locus tagDA416_09385Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_PZQZ01000003.1Sequence record reported by the local genomic context database.
Genomic interval1 939 386-1 941 380 nt1 995 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1 939 386-1 942 702 ntGCF_006380835::NZ_PZQZ01000003.1::G00028

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_006380835::NZ_PZQZ01000003.1::G00028

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_PZQZ01000003.1All displayed genes belong to this local TCS context.
Neighborhood span1 939 386-1 942 702 nt3 317 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 939 386 nt1 942 702 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DA416_RS09375GCF_006380835#DA416_RS09375
HKClassicCurrent focus

1 939 386-1 941 380 nt · Forward (+)

Old locus DA416_09385RefSeq WP_021411151.1
DA416_RS09380GCF_006380835#DA416_RS09380
RRNtrC

1 941 380-1 942 702 nt · Forward (+)

Old locus DA416_09390RefSeq WP_004454409.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0860374Run 6 · HK · 25 sequences
Representative sequenceGCF_000450445#QKY_RS08315Use this link to inspect the representative gene detail.
PFAM architectureSBP_bac_3 + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0860374

Simplified PFAM architecture for HKOC_0860374

PFAM domain coverage: 385 / 664 aa (58.0%)

1 aa664 aa
SBP_bac_3: 60-277 aaSBP_bac_3HisKA: 448-509 aaHisKAHATPase_c: 555-659 aaHATPase_c
SBP_bac_3HisKAHATPase_c
  • Simplified architecture: SBP_bac_3 + HisKA + HATPase_c
  • Raw architecture: SBP_bac_3[60-277] | HisKA[448-509] | HATPase_c[555-659]
  • Domain count: 3
  • Matched identifier: HKOC_0860374
  • Positioned domains: SBP_bac_3 60-277 ; HisKA 448-509 ; HATPase_c 555-659
Cluster members and taxonomy
Visualization

Representative gene: GCF_000450445#QKY_RS08315

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_006380835
AssemblyASM638083v1 · Contighaploid
Genome composition4 135 554 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 99 · HK 47 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key