Gene detail

DA414_RS10305

Histidine kinase, Classic

Clostridioides difficile · GCF_006379335

ClassHKTypeClassicLength343 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_006379335#DA414_RS10305Stable P2CS identifier used across views.
GenomeGCF_006379335Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2827962Run 6 · 300 sequences · id 100% · cov 80%
External referencesWP_021363597.1 · MIST4 DA414_RS10305RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length343 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage167 / 343 aa (48.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa343 aa
HisKA: 124-189 aa (66 aa)1HATPase_c: 241-341 aa (101 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
124-189 aa · 66 aa · 19.2% of protein
Raw tokenHisKA:124:0.000000341:189:66:64
2 HATPase_c#2
241-341 aa · 101 aa · 29.4% of protein
Raw tokenHATPase_c:241:5.71e-24:341:101:109
  • Raw architecture: HisKA:124:0.000000341:189:66:64#HATPase_c:241:5.71e-24:341:101:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_006379335::NZ_PZQX01000002.1::G00036
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2134396-2136103Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDA414_10305RefSeq proteinWP_021363597.1
Context group IDGCF_006379335::NZ_PZQX01000002.1::G00036
Context members
DA414_RS10300DA414_RS10305
Partner locus tags
DA414_RS10300DA414_RS10305
Partner old locus tags
DA414_10300DA414_10305
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021363597.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDA414_RS10305Primary locus identifier stored in the genes table.
Old locus tagDA414_10305Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_PZQX01000002.1Sequence record reported by the local genomic context database.
Genomic interval2 135 072-2 136 103 nt1 032 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span2 134 396-2 136 103 ntGCF_006379335::NZ_PZQX01000002.1::G00036

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_006379335::NZ_PZQX01000002.1::G00036

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_PZQX01000002.1All displayed genes belong to this local TCS context.
Neighborhood span2 134 396-2 136 103 nt1 708 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 134 396 nt2 136 103 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DA414_RS10300GCF_006379335#DA414_RS10300
RROmpR

2 134 396-2 135 082 nt · Forward (+)

Old locus DA414_10300RefSeq WP_011861401.1
DA414_RS10305GCF_006379335#DA414_RS10305
HKClassicCurrent focus

2 135 072-2 136 103 nt · Forward (+)

Old locus DA414_10305RefSeq WP_021363597.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2827962Run 6 · HK · 300 sequences
Representative sequenceGCF_000448905#QAY_RS09450Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2827962

Simplified PFAM architecture for HKOC_2827962

PFAM domain coverage: 173 / 343 aa (50.4%)

1 aa343 aa
HisKA: 124-189 aaHisKAHATPase_c: 236-342 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[124-189] | HATPase_c[236-342]
  • Domain count: 2
  • Matched identifier: HKOC_2827962
  • Positioned domains: HisKA 124-189 ; HATPase_c 236-342
Cluster members and taxonomy
Visualization

Representative gene: GCF_000448905#QAY_RS09450

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_006379335
AssemblyASM637933v1 · Contighaploid
Genome composition4 107 083 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 100 · HK 47 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key