Gene detail

E5F35_RS07265

Response regulator, RpfG family

Clostridioides difficile · GCF_004684595

ClassRRTypeRpfGLength546 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_004684595#E5F35_RS07265Stable P2CS identifier used across views.
GenomeGCF_004684595Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterRROC_0079329Run 7 · 118 sequences · id 100% · cov 80%
External referencesWP_009901919.1 · A0AB74QCM1 · MIST4 E5F35_RS07265RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

Response_regHDGGDEF
Protein length546 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage356 / 546 aa (65.2%)Merged over positioned domains only.
Domain description1 Response_reg,1 HD,1 GGDEFSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa546 aa
Response_reg: 6-110 aa (105 aa)1HD: 195-300 aa (106 aa)2GGDEF: 384-528 aa (145 aa)3
Domain-by-domain annotation3 items
1 Response_reg#1
6-110 aa · 105 aa · 19.2% of protein
Raw tokenResponse_reg:6:5.98e-27:110:106:111
2 HD#2
195-300 aa · 106 aa · 19.4% of protein
Raw tokenHD:195:0.00000000000785:300:106:110
3 GGDEF#3
384-528 aa · 145 aa · 26.6% of protein
Raw tokenGGDEF:384:3.37e-40:528:162:160
  • Raw architecture: Response_reg:6:5.98e-27:110:106:111#HD:195:0.00000000000785:300:106:110#GGDEF:384:3.37e-40:528:162:160
  • Domain description: 1 Response_reg,1 HD,1 GGDEF
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_004684595::NZ_SRKJ01000054.1::G00038
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span13197-17765Genomic interval covered by the local TCS group.
Identifiers
Old locus tagE5F35_07270RefSeq proteinWP_009901919.1
Context group IDGCF_004684595::NZ_SRKJ01000054.1::G00038
Context members
E5F35_RS07265E5F35_RS07275
Partner locus tags
E5F35_RS07265E5F35_RS07275
Partner old locus tags
E5F35_07270E5F35_07280
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009901919.1Primary protein accession used for annex mappings.
UniProt accessionA0AB74QCM1Primary UniProt accession resolved in the annex database.
UniProt IDA0AB74QCM1_CLODIDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagE5F35_RS07265Primary locus identifier stored in the genes table.
Old locus tagE5F35_07270Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_SRKJ01000054.1Sequence record reported by the local genomic context database.
Genomic interval13 197-14 837 nt1 641 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span13 197-17 765 ntGCF_004684595::NZ_SRKJ01000054.1::G00038

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_004684595::NZ_SRKJ01000054.1::G00038

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_SRKJ01000054.1All displayed genes belong to this local TCS context.
Neighborhood span13 197-17 765 nt4 569 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
13 197 nt17 765 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

E5F35_RS07265GCF_004684595#E5F35_RS07265
RRRpfGCurrent focus

13 197-14 837 nt · Forward (+)

Old locus E5F35_07270RefSeq WP_009901919.1
E5F35_RS07275GCF_004684595#E5F35_RS07275
HKHybrid

15 207-17 765 nt · Forward (+)

Old locus E5F35_07280RefSeq WP_025992016.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterRROC_0079329Run 7 · RR · 118 sequences
Representative sequenceGCF_000155025#UAB_RS0203460Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + HD_5 + GGDEF3 domains in the representative PFAM annotation.

PFAM architecture for RROC_0079329

Simplified PFAM architecture for RROC_0079329

PFAM domain coverage: 385 / 546 aa (70.5%)

1 aa546 aa
Response_reg: 6-117 aaResponse_regResponse_reg: 6-117 aaResponse_regHD_5: 191-320 aaHD_5HD_5: 191-320 aaHD_5GGDEF: 384-526 aaGGDEFGGDEF: 384-526 aaGGDEF
Response_regHD_5GGDEF
  • Simplified architecture: Response_reg + HD_5 + GGDEF
  • Raw architecture: Response_reg[6-117] | HD_5[191-320] | GGDEF[384-526]
  • Domain count: 3
  • Matched identifier: RROC_0079329
  • Positioned domains: Response_reg 6-117 ; Response_reg 6-117 ; HD_5 191-320 ; HD_5 191-320 ; GGDEF 384-526 ; GGDEF 384-526
Cluster members and taxonomy
Visualization

Representative gene: GCF_000155025#UAB_RS0203460

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_004684595
AssemblyASM468459v1 · Contighaploid
Genome composition4 252 418 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 102 · HK 49 · RR 52CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key