1 HisKA#1
85-154 aa · 70 aa · 23.0% of protein
Raw token
HisKA:85:0.00000000000195:154:70:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
E5F35_RS01140
Histidine kinase, Classic
Clostridioides difficile · GCF_004684595
ClassHKTypeClassicLength305 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_004684595#E5F35_RS01140Stable P2CS identifier used across views.
GenomeGCF_004684595Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length305 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage174 / 305 aa (57.0%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa305 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
201-304 aa · 104 aa · 34.1% of protein
Raw token
HATPase_c:201:1.04e-27:304:106:109- Raw architecture: HisKA:85:0.00000000000195:154:70:64#HATPase_c:201:1.04e-27:304:106:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_004684595::NZ_SRKJ01000018.1::G00017
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span36191-37797Genomic interval covered by the local TCS group.
Identifiers
Old locus tagE5F35_01145RefSeq proteinWP_009902054.1
Context group ID
GCF_004684595::NZ_SRKJ01000018.1::G00017Context members
E5F35_RS01140E5F35_RS01145
Partner locus tags
E5F35_RS01140E5F35_RS01145
Partner old locus tags
E5F35_01145E5F35_01150
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_009902054.1Primary protein accession used for annex mappings.
UniProt accessionA0AB74QBZ4Primary UniProt accession resolved in the annex database.
UniProt IDA0AB74QBZ4_CLODIDisplay identifier provided by UniProt.
GO / PubMed1 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagE5F35_RS01140Primary locus identifier stored in the genes table.
Old locus tagE5F35_01145Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_SRKJ01000018.1Sequence record reported by the local genomic context database.
Genomic interval36 191-37 108 nt918 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span36 191-37 797 ntGCF_004684595::NZ_SRKJ01000018.1::G00017
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_004684595::NZ_SRKJ01000018.1::G00017Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_SRKJ01000018.1All displayed genes belong to this local TCS context.
Neighborhood span36 191-37 797 nt1 607 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
36 191 nt37 797 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
E5F35_RS01140GCF_004684595#E5F35_RS01140
HKClassicCurrent focus
36 191-37 108 nt · Reverse (-)
E5F35_RS01145GCF_004684595#E5F35_RS01145
RROmpR
37 108-37 797 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000155025#UAB_RS0204305Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2882002
Simplified PFAM architecture for HKOC_2882002
PFAM domain coverage: 171 / 305 aa (56.1%)
1 aa305 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[88-154] | HATPase_c[201-304]
- Domain count: 2
- Matched identifier: HKOC_2882002
- Positioned domains: HisKA 88-154 ; HATPase_c 201-304
Cluster members and taxonomy
Representative gene: GCF_000155025#UAB_RS0204305
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_004684595
AssemblyASM468459v1 · Contighaploid
Genome composition4 252 418 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 102 · HK 49 · RR 52CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key