1 HisKA#1
234-299 aa · 66 aa · 14.5% of protein
Raw token
HisKA:234:0.00000000000000218:299:66:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
E5F36_RS00345
Histidine kinase, Classic
Clostridioides difficile · GCF_004684575
ClassHKTypeClassicLength454 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_004684575#E5F36_RS00345Stable P2CS identifier used across views.
GenomeGCF_004684575Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length454 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage177 / 454 aa (39.0%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa454 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
344-454 aa · 111 aa · 24.4% of protein
Raw token
HATPase_c:344:9.85e-22:454:111:109- Raw architecture: HisKA:234:0.00000000000000218:299:66:64#HATPase_c:344:9.85e-22:454:111:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_004684575::NZ_SRKI01000008.1::G00061
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span24250-26264Genomic interval covered by the local TCS group.
Identifiers
Old locus tagE5F36_00345RefSeq proteinWP_032544554.1
Context group ID
GCF_004684575::NZ_SRKI01000008.1::G00061Context members
E5F36_RS00340E5F36_RS00345
Partner locus tags
E5F36_RS00340E5F36_RS00345
Partner old locus tags
E5F36_00340E5F36_00345
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_032544554.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagE5F36_RS00345Primary locus identifier stored in the genes table.
Old locus tagE5F36_00345Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_SRKI01000008.1Sequence record reported by the local genomic context database.
Genomic interval24 900-26 264 nt1 365 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span24 250-26 264 ntGCF_004684575::NZ_SRKI01000008.1::G00061
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_004684575::NZ_SRKI01000008.1::G00061Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_SRKI01000008.1All displayed genes belong to this local TCS context.
Neighborhood span24 250-26 264 nt2 015 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
24 250 nt26 264 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
E5F36_RS00340GCF_004684575#E5F36_RS00340
RROmpR
24 250-24 909 nt · Forward (+)
E5F36_RS00345GCF_004684575#E5F36_RS00345
HKClassicCurrent focus
24 900-26 264 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000450605#QME_RS15750Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1912643
Simplified PFAM architecture for HKOC_1912643
PFAM domain coverage: 177 / 454 aa (39.0%)
1 aa454 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[234-299] | HATPase_c[344-454]
- Domain count: 2
- Matched identifier: HKOC_1912643
- Positioned domains: HisKA 234-299 ; HATPase_c 344-454
Cluster members and taxonomy
Representative gene: GCF_000450605#QME_RS15750
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_004684575
AssemblyASM468457v1 · Contighaploid
Genome composition4 238 854 bp · 28,0% GCClostridioides difficile
Signal transduction countsGenes 104 · HK 49 · RR 55CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key