Gene detail

E5F26_RS05140

Histidine kinase, Classic

Clostridioides difficile · GCF_004684385

ClassHKTypeClassicLength387 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_004684385#E5F26_RS05140Stable P2CS identifier used across views.
GenomeGCF_004684385Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2453446Run 6 · 200 sequences · id 100% · cov 80%
External referencesWP_021373389.1 · MIST4 E5F26_RS05140RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKA_3HATPase_c
Protein length387 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage151 / 387 aa (39.0%)Merged over positioned domains only.
Domain description1 HisKA_3,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa387 aa
HisKA_3: 188-253 aa (66 aa)1HATPase_c: 294-378 aa (85 aa)2
Domain-by-domain annotation2 items
1 HisKA_3#1
188-253 aa · 66 aa · 17.1% of protein
Raw tokenHisKA_3:188:3.27e-20:253:67:68
2 HATPase_c#2
294-378 aa · 85 aa · 22.0% of protein
Raw tokenHATPase_c:294:0.00000000777:378:104:109
  • Raw architecture: HisKA_3:188:3.27e-20:253:67:68#HATPase_c:294:0.00000000777:378:104:109
  • Domain description: 1 HisKA_3,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_004684385::NZ_SRJS01000048.1::G00048
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span79245-81048Genomic interval covered by the local TCS group.
Identifiers
Old locus tagE5F26_05140RefSeq proteinWP_021373389.1
Context group IDGCF_004684385::NZ_SRJS01000048.1::G00048
Context members
E5F26_RS05140E5F26_RS05145
Partner locus tags
E5F26_RS05140E5F26_RS05145
Partner old locus tags
E5F26_05140E5F26_05145
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021373389.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagE5F26_RS05140Primary locus identifier stored in the genes table.
Old locus tagE5F26_05140Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_SRJS01000048.1Sequence record reported by the local genomic context database.
Genomic interval79 245-80 408 nt1 164 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span79 245-81 048 ntGCF_004684385::NZ_SRJS01000048.1::G00048

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_004684385::NZ_SRJS01000048.1::G00048

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_SRJS01000048.1All displayed genes belong to this local TCS context.
Neighborhood span79 245-81 048 nt1 804 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
79 245 nt81 048 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

E5F26_RS05140GCF_004684385#E5F26_RS05140
HKClassicCurrent focus

79 245-80 408 nt · Forward (+)

Old locus E5F26_05140RefSeq WP_021373389.1
E5F26_RS05145GCF_004684385#E5F26_RS05145
RRNarL

80 401-81 048 nt · Forward (+)

Old locus E5F26_05145RefSeq WP_021373388.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2453446Run 6 · HK · 200 sequences
Representative sequenceGCF_004318545#E0R11_RS17805Use this link to inspect the representative gene detail.
PFAM architectureHisKA_3 + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2453446

Simplified PFAM architecture for HKOC_2453446

PFAM domain coverage: 150 / 399 aa (37.6%)

1 aa399 aa
HisKA_3: 200-264 aaHisKA_3HATPase_c: 306-390 aaHATPase_c
HisKA_3HATPase_c
  • Simplified architecture: HisKA_3 + HATPase_c
  • Raw architecture: HisKA_3[200-264] | HATPase_c[306-390]
  • Domain count: 2
  • Matched identifier: HKOC_2453446
  • Positioned domains: HisKA_3 200-264 ; HATPase_c 306-390
Cluster members and taxonomy
Visualization

Representative gene: GCF_004318545#E0R11_RS17805

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_004684385
AssemblyASM468438v1 · Contighaploid
Genome composition4 253 251 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 103 · HK 48 · RR 55CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key