Gene detail

E0R48_RS18670

Histidine kinase, Classic

Clostridioides difficile · GCF_004319405

ClassHKTypeClassicLength656 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_004319405#E0R48_RS18670Stable P2CS identifier used across views.
GenomeGCF_004319405Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0860920Run 6 · 25 sequences · id 100% · cov 80%
External referencesWP_131068741.1 · MIST4 E0R48_RS18670RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

SBP_bac_3HisKAHATPase_c
Protein length656 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage386 / 656 aa (58.8%)Merged over positioned domains only.
Domain description1 SBP_bac_3,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa656 aa
SBP_bac_3: 50-270 aa (221 aa)1HisKA: 438-500 aa (63 aa)2HATPase_c: 549-650 aa (102 aa)3
Domain-by-domain annotation3 items
1 SBP_bac_3#1
50-270 aa · 221 aa · 33.7% of protein
Raw tokenSBP_bac_3:50:4.17e-41:270:230:224
2 HisKA#2
438-500 aa · 63 aa · 9.6% of protein
Raw tokenHisKA:438:0.0000000000000467:500:63:64
3 HATPase_c#3
549-650 aa · 102 aa · 15.5% of protein
Raw tokenHATPase_c:549:2.49e-23:650:103:109
  • Raw architecture: SBP_bac_3:50:4.17e-41:270:230:224#HisKA:438:0.0000000000000467:500:63:64#HATPase_c:549:2.49e-23:650:103:109
  • Domain description: 1 SBP_bac_3,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_004319405::NZ_BIXV01000259.1::G00053
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1-3037Genomic interval covered by the local TCS group.
Context group IDGCF_004319405::NZ_BIXV01000259.1::G00053
Context members
E0R48_RS18670E0R48_RS18675
Partner locus tags
E0R48_RS18670E0R48_RS18675
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_131068741.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagE0R48_RS18670Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_BIXV01000259.1Sequence record reported by the local genomic context database.
Genomic interval1-1 971 nt1 971 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1-3 037 ntGCF_004319405::NZ_BIXV01000259.1::G00053

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_004319405::NZ_BIXV01000259.1::G00053

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_BIXV01000259.1All displayed genes belong to this local TCS context.
Neighborhood span1-3 037 nt3 037 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 nt3 037 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

E0R48_RS18675GCF_004319405#E0R48_RS18675
RRunclassified

1 971-3 037 nt · Forward (+)

RefSeq WP_131068742.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0860920Run 6 · HK · 25 sequences
Representative sequenceGCF_002301905#BGU50_RS13910Use this link to inspect the representative gene detail.
PFAM architectureSBP_bac_3 + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0860920

Simplified PFAM architecture for HKOC_0860920

PFAM domain coverage: 385 / 664 aa (58.0%)

1 aa664 aa
SBP_bac_3: 60-277 aaSBP_bac_3HisKA: 448-509 aaHisKAHATPase_c: 555-659 aaHATPase_c
SBP_bac_3HisKAHATPase_c
  • Simplified architecture: SBP_bac_3 + HisKA + HATPase_c
  • Raw architecture: SBP_bac_3[60-277] | HisKA[448-509] | HATPase_c[555-659]
  • Domain count: 3
  • Matched identifier: HKOC_0860920
  • Positioned domains: SBP_bac_3 60-277 ; HisKA 448-509 ; HATPase_c 555-659
Cluster members and taxonomy
Visualization

Representative gene: GCF_002301905#BGU50_RS13910

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_004319405
AssemblyASM431940v1 · Scaffoldhaploid
Genome composition4 057 697 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 94 · HK 45 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key