Gene detail

E0R48_RS00585

Histidine kinase, Classic

Clostridioides difficile · GCF_004319405

ClassHKTypeClassicLength462 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_004319405#E0R48_RS00585Stable P2CS identifier used across views.
GenomeGCF_004319405Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1809825Run 6 · 23 sequences · id 100% · cov 80%
External referencesWP_070538172.1 · MIST4 E0R48_RS00585RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length462 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage174 / 462 aa (37.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for E0R48_RS00585
Domain-by-domain annotation2 items
1 HisKA#1
241-305 aa · 65 aa · 14.1% of protein
Raw tokenHisKA:241:0.00000000000139:305:65:64
2 HATPase_c#2
352-460 aa · 109 aa · 23.6% of protein
Raw tokenHATPase_c:352:5.06e-21:460:109:109
  • Raw architecture: HisKA:241:0.00000000000139:305:65:64#HATPase_c:352:5.06e-21:460:109:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_004319405::NZ_BIXV01000002.1::G00002
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span2529-3917Genomic interval covered by the local TCS group.
Context group IDGCF_004319405::NZ_BIXV01000002.1::G00002
Context members
E0R48_RS00585
Partner locus tags
E0R48_RS00585
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_070538172.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagE0R48_RS00585Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_BIXV01000002.1Sequence record reported by the local genomic context database.
Genomic interval2 529-3 917 nt1 389 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span2 529-3 917 ntGCF_004319405::NZ_BIXV01000002.1::G00002

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_004319405::NZ_BIXV01000002.1::G00002

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_BIXV01000002.1All displayed genes belong to this local TCS context.
Neighborhood span2 529-3 917 nt1 389 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 529 nt3 917 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1809825Run 6 · HK · 23 sequences
Representative sequenceGCF_002301905#BGU50_RS14660Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1809825

Simplified PFAM architecture for HKOC_1809825

PFAM domain coverage: 174 / 462 aa (37.7%)

1 aa462 aa
HisKA: 241-305 aaHisKAHATPase_c: 352-460 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[241-305] | HATPase_c[352-460]
  • Domain count: 2
  • Matched identifier: HKOC_1809825
  • Positioned domains: HisKA 241-305 ; HATPase_c 352-460
Cluster members and taxonomy
Visualization

Representative gene: GCF_002301905#BGU50_RS14660

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_004319405
AssemblyASM431940v1 · Scaffoldhaploid
Genome composition4 057 697 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 94 · HK 45 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key