Gene detail

E0R25_RS13885

Histidine kinase, Classic

Clostridioides difficile · GCF_004318825

ClassHKTypeClassicLength482 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_004318825#E0R25_RS13885Stable P2CS identifier used across views.
GenomeGCF_004318825Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1359832Run 6 · 388 sequences · id 100% · cov 80%
External referencesWP_131064610.1 · MIST4 E0R25_RS13885RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length482 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage153 / 482 aa (31.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa482 aa
HisKA: 261-327 aa (67 aa)1HATPase_c: 380-465 aa (86 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
261-327 aa · 67 aa · 13.9% of protein
Raw tokenHisKA:261:0.0000000000000115:327:67:64
2 HATPase_c#2
380-465 aa · 86 aa · 17.8% of protein
Raw tokenHATPase_c:380:0.0000000457:465:90:109
  • Raw architecture: HisKA:261:0.0000000000000115:327:67:64#HATPase_c:380:0.0000000457:465:90:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_004318825::NZ_BIWS01000133.1::G00039
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span9865-11313Genomic interval covered by the local TCS group.
Context group IDGCF_004318825::NZ_BIWS01000133.1::G00039
Context members
E0R25_RS13885
Partner locus tags
E0R25_RS13885
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_131064610.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagE0R25_RS13885Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_BIWS01000133.1Sequence record reported by the local genomic context database.
Genomic interval9 865-11 313 nt1 449 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span9 865-11 313 ntGCF_004318825::NZ_BIWS01000133.1::G00039

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_004318825::NZ_BIWS01000133.1::G00039

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_BIWS01000133.1All displayed genes belong to this local TCS context.
Neighborhood span9 865-11 313 nt1 449 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
9 865 nt11 313 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1359832Run 6 · HK · 388 sequences
Representative sequenceGCF_000448905#QAY_RS11350Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1359832

Simplified PFAM architecture for HKOC_1359832

PFAM domain coverage: 191 / 529 aa (36.1%)

1 aa529 aa
HAMP: 254-294 aaHAMPHisKA: 309-374 aaHisKAHATPase_c: 426-509 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[254-294] | HisKA[309-374] | HATPase_c[426-509]
  • Domain count: 3
  • Matched identifier: HKOC_1359832
  • Positioned domains: HAMP 254-294 ; HisKA 309-374 ; HATPase_c 426-509
Cluster members and taxonomy
Visualization

Representative gene: GCF_000448905#QAY_RS11350

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_004318825
AssemblyASM431882v1 · Scaffoldhaploid
Genome composition4 112 375 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 97 · HK 48 · RR 47CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key