Gene detail

E0R01_RS10945

Histidine kinase, Classic

Clostridioides difficile · GCF_004318605

ClassHKTypeClassicLength215 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_004318605#E0R01_RS10945Stable P2CS identifier used across views.
GenomeGCF_004318605Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2929988Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_254216621.1 · MIST4 E0R01_RS10945RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKA_3HATPase_c
Protein length215 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage151 / 215 aa (70.2%)Merged over positioned domains only.
Domain description1 HisKA_3,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa215 aa
HisKA_3: 16-81 aa (66 aa)1HATPase_c: 122-206 aa (85 aa)2
Domain-by-domain annotation2 items
1 HisKA_3#1
16-81 aa · 66 aa · 30.7% of protein
Raw tokenHisKA_3:16:1.67e-20:81:67:68
2 HATPase_c#2
122-206 aa · 85 aa · 39.5% of protein
Raw tokenHATPase_c:122:0.0000000000913:206:104:109
  • Raw architecture: HisKA_3:16:1.67e-20:81:67:68#HATPase_c:122:0.0000000000913:206:104:109
  • Domain description: 1 HisKA_3,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_004318605::NZ_BIWH01000108.1::G00023
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span10664-11951Genomic interval covered by the local TCS group.
Context group IDGCF_004318605::NZ_BIWH01000108.1::G00023
Context members
E0R01_RS10940E0R01_RS10945
Partner locus tags
E0R01_RS10940E0R01_RS10945
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_254216621.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagE0R01_RS10945Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_BIWH01000108.1Sequence record reported by the local genomic context database.
Genomic interval11 304-11 951 nt648 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span10 664-11 951 ntGCF_004318605::NZ_BIWH01000108.1::G00023

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_004318605::NZ_BIWH01000108.1::G00023

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_BIWH01000108.1All displayed genes belong to this local TCS context.
Neighborhood span10 664-11 951 nt1 288 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
10 664 nt11 951 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

E0R01_RS10940GCF_004318605#E0R01_RS10940
RRNarL

10 664-11 311 nt · Reverse (-)

RefSeq WP_009896181.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2929988Run 6 · HK · 1 sequences
Representative sequenceGCF_004318605#E0R01_RS10945The current gene is the representative for this cluster.
PFAM architectureHisKA_3 + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2929988

Simplified PFAM architecture for HKOC_2929988

PFAM domain coverage: 150 / 215 aa (69.8%)

1 aa215 aa
HisKA_3: 16-80 aaHisKA_3HATPase_c: 122-206 aaHATPase_c
HisKA_3HATPase_c
  • Simplified architecture: HisKA_3 + HATPase_c
  • Raw architecture: HisKA_3[16-80] | HATPase_c[122-206]
  • Domain count: 2
  • Matched identifier: HKOC_2929988
  • Positioned domains: HisKA_3 16-80 ; HATPase_c 122-206
Cluster members and taxonomy
Visualization

Representative gene: GCF_004318605#E0R01_RS10945

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_004318605
AssemblyASM431860v1 · Scaffoldhaploid
Genome composition3 926 314 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 89 · HK 43 · RR 46CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key