Gene detail

E0R01_RS09610

Histidine kinase, Classic

Clostridioides difficile · GCF_004318605

ClassHKTypeClassicLength313 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_004318605#E0R01_RS09610Stable P2CS identifier used across views.
GenomeGCF_004318605Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0878348Run 6 · 1724 sequences · id 100% · cov 80%
External referencesWP_131043880.1 · MIST4 E0R01_RS09610RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKA_2HATPase_c
Protein length313 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage173 / 313 aa (55.3%)Merged over positioned domains only.
Domain description1 HisKA_2,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa313 aa
HisKA_2: 120-194 aa (75 aa)1HATPase_c: 214-311 aa (98 aa)2
Domain-by-domain annotation2 items
1 HisKA_2#1
120-194 aa · 75 aa · 24.0% of protein
Raw tokenHisKA_2:120:2.52e-16:194:76:76
2 HATPase_c#2
214-311 aa · 98 aa · 31.3% of protein
Raw tokenHATPase_c:214:0.0000000952:311:114:109
  • Raw architecture: HisKA_2:120:2.52e-16:194:76:76#HATPase_c:214:0.0000000952:311:114:109
  • Domain description: 1 HisKA_2,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_004318605::NZ_BIWH01000088.1::G00020
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span1-944Genomic interval covered by the local TCS group.
Context group IDGCF_004318605::NZ_BIWH01000088.1::G00020
Context members
E0R01_RS09610
Partner locus tags
E0R01_RS09610
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_131043880.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagE0R01_RS09610Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_BIWH01000088.1Sequence record reported by the local genomic context database.
Genomic interval1-944 nt944 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1-944 ntGCF_004318605::NZ_BIWH01000088.1::G00020

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_004318605::NZ_BIWH01000088.1::G00020

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_BIWH01000088.1All displayed genes belong to this local TCS context.
Neighborhood span1-944 nt944 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 nt944 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0878348Run 6 · HK · 1724 sequences
Representative sequenceGCF_041537345#ACD536_RS00630Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + ANTAR + GAF_PdtaS + HisKA_2 + HATPase_c5 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0878348

Simplified PFAM architecture for HKOC_0878348

PFAM domain coverage: 466 / 658 aa (70.8%)

1 aa658 aa
Response_reg: 5-115 aaResponse_regANTAR: 134-186 aaANTARGAF_PdtaS: 195-330 aaGAF_PdtaSHisKA_2: 465-536 aaHisKA_2HATPase_c: 562-655 aaHATPase_c
Response_regANTARGAF_PdtaSHisKA_2HATPase_c
  • Simplified architecture: Response_reg + ANTAR + GAF_PdtaS + HisKA_2 + HATPase_c
  • Raw architecture: Response_reg[5-115] | ANTAR[134-186] | GAF_PdtaS[195-330] | HisKA_2[465-536] | HATPase_c[562-655]
  • Domain count: 5
  • Matched identifier: HKOC_0878348
  • Positioned domains: Response_reg 5-115 ; ANTAR 134-186 ; GAF_PdtaS 195-330 ; HisKA_2 465-536 ; HATPase_c 562-655
Cluster members and taxonomy
Visualization

Representative gene: GCF_041537345#ACD536_RS00630

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_004318605
AssemblyASM431860v1 · Scaffoldhaploid
Genome composition3 926 314 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 89 · HK 43 · RR 46CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key