Gene detail

E0Q96_RS17595

Histidine kinase, Classic

Clostridioides difficile · GCF_004318565

ClassHKTypeClassicLength293 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_004318565#E0Q96_RS17595Stable P2CS identifier used across views.
GenomeGCF_004318565Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1783726Run 6 · 289 sequences · id 100% · cov 80%
External referencesWP_254190941.1 · MIST4 E0Q96_RS17595RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length293 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage211 / 293 aa (72.0%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa293 aa
HAMP: 1-66 aa (66 aa)1HisKA: 78-137 aa (60 aa)2HATPase_c: 184-268 aa (85 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
1-66 aa · 66 aa · 22.5% of protein
Raw tokenHAMP:1:0.000000000058:66:66:69
2 HisKA#2
78-137 aa · 60 aa · 20.5% of protein
Raw tokenHisKA:78:0.000000000266:137:61:64
3 HATPase_c#3
184-268 aa · 85 aa · 29.0% of protein
Raw tokenHATPase_c:184:6.77e-16:268:88:109
  • Raw architecture: HAMP:1:0.000000000058:66:66:69#HisKA:78:0.000000000266:137:61:64#HATPase_c:184:6.77e-16:268:88:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_004318565::NZ_BIWF01000042.1::G00017
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span18614-19495Genomic interval covered by the local TCS group.
Context group IDGCF_004318565::NZ_BIWF01000042.1::G00017
Context members
E0Q96_RS17595
Partner locus tags
E0Q96_RS17595
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_254190941.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagE0Q96_RS17595Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_BIWF01000042.1Sequence record reported by the local genomic context database.
Genomic interval18 614-19 495 nt882 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span18 614-19 495 ntGCF_004318565::NZ_BIWF01000042.1::G00017

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_004318565::NZ_BIWF01000042.1::G00017

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_BIWF01000042.1All displayed genes belong to this local TCS context.
Neighborhood span18 614-19 495 nt882 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
18 614 nt19 495 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1783726Run 6 · HK · 289 sequences
Representative sequenceGCF_000155065#QAE_RS0202465Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1783726

Simplified PFAM architecture for HKOC_1783726

PFAM domain coverage: 195 / 464 aa (42.0%)

1 aa464 aa
HAMP: 187-236 aaHAMPHisKA: 250-308 aaHisKAHATPase_c: 355-440 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[187-236] | HisKA[250-308] | HATPase_c[355-440]
  • Domain count: 3
  • Matched identifier: HKOC_1783726
  • Positioned domains: HAMP 187-236 ; HisKA 250-308 ; HATPase_c 355-440
Cluster members and taxonomy
Visualization

Representative gene: GCF_000155065#QAE_RS0202465

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_004318565
AssemblyASM431856v1 · Scaffoldhaploid
Genome composition3 643 242 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 92 · HK 46 · RR 46CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key