Gene detail

E0Q96_RS01290

Histidine kinase, Classic

Clostridioides difficile · GCF_004318565

ClassHKTypeClassicLength311 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_004318565#E0Q96_RS01290Stable P2CS identifier used across views.
GenomeGCF_004318565Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2876393Run 6 · 306 sequences · id 100% · cov 80%
External referencesWP_003418502.1 · D5Q150 · MIST4 E0Q96_RS01290RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length311 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage170 / 311 aa (54.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa311 aa
HisKA: 94-156 aa (63 aa)1HATPase_c: 204-310 aa (107 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
94-156 aa · 63 aa · 20.3% of protein
Raw tokenHisKA:94:0.000000179:156:63:64
2 HATPase_c#2
204-310 aa · 107 aa · 34.4% of protein
Raw tokenHATPase_c:204:8.4e-31:310:107:109
  • Raw architecture: HisKA:94:0.000000179:156:63:64#HATPase_c:204:8.4e-31:310:107:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_004318565::NZ_BIWF01000007.1::G00003
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span28567-30191Genomic interval covered by the local TCS group.
Context group IDGCF_004318565::NZ_BIWF01000007.1::G00003
Context members
E0Q96_RS01285E0Q96_RS01290
Partner locus tags
E0Q96_RS01285E0Q96_RS01290
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003418502.1Primary protein accession used for annex mappings.
UniProt accessionD5Q150Primary UniProt accession resolved in the annex database.
UniProt IDD5Q150_CLODIDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagE0Q96_RS01290Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_BIWF01000007.1Sequence record reported by the local genomic context database.
Genomic interval29 256-30 191 nt936 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span28 567-30 191 ntGCF_004318565::NZ_BIWF01000007.1::G00003

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_004318565::NZ_BIWF01000007.1::G00003

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_BIWF01000007.1All displayed genes belong to this local TCS context.
Neighborhood span28 567-30 191 nt1 625 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
28 567 nt30 191 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

E0Q96_RS01285GCF_004318565#E0Q96_RS01285
RROmpR

28 567-29 259 nt · Forward (+)

RefSeq WP_009905133.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2876393Run 6 · HK · 306 sequences
Representative sequenceGCF_000155065#QAE_RS0204125Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2876393

Simplified PFAM architecture for HKOC_2876393

PFAM domain coverage: 170 / 311 aa (54.7%)

1 aa311 aa
HisKA: 93-155 aaHisKAHATPase_c: 204-310 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[93-155] | HATPase_c[204-310]
  • Domain count: 2
  • Matched identifier: HKOC_2876393
  • Positioned domains: HisKA 93-155 ; HATPase_c 204-310
Cluster members and taxonomy
Visualization

Representative gene: GCF_000155065#QAE_RS0204125

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 306 total members. Page 1 / 7.

GCF_000155065#QAE_RS0204125 (representative)
QAE_RS0204125 · HK · Classic
RefSeq: WP_003418502.1
UniProt: D5Q150
GCF_000164175#HMPREF0220_RS07295
HMPREF0220_RS07295 · HK · Classic
RefSeq: WP_003418502.1
UniProt: D5Q150
GCF_000164655#HMPREF0219_RS07395
HMPREF0219_RS07395 · HK · Classic
RefSeq: WP_003418502.1
UniProt: D5Q150
GCF_000210435#CDM120_RS04790
CDM120_RS04790 · HK · Classic
RefSeq: WP_003418502.1
UniProt: D5Q150
GCF_000499505#BN164_RS04285
BN164_RS04285 · HK · Classic
RefSeq: WP_003418502.1
UniProt: D5Q150
GCF_000531165#BN166_RS13150
BN166_RS13150 · HK · Classic
RefSeq: WP_003418502.1
UniProt: D5Q150
GCF_000582865#BN165_RS03885
BN165_RS03885 · HK · Classic
RefSeq: WP_003418502.1
UniProt: D5Q150
GCF_001050575#BN163_RS03940
BN163_RS03940 · HK · Classic
RefSeq: WP_003418502.1
UniProt: D5Q150
GCF_001972065#BER35_RS04950
BER35_RS04950 · HK · Classic
RefSeq: WP_003418502.1
UniProt: D5Q150
GCF_001972115#BER34_RS17790
BER34_RS17790 · HK · Classic
RefSeq: WP_003418502.1
UniProt: D5Q150
GCF_002301695#BGU20_RS11215
BGU20_RS11215 · HK · Classic
RefSeq: WP_003418502.1
UniProt: D5Q150
GCF_002302685#BGU93_RS00590
BGU93_RS00590 · HK · Classic
RefSeq: WP_003418502.1
UniProt: D5Q150
GCF_002303305#BGU53_RS06180
BGU53_RS06180 · HK · Classic
RefSeq: WP_003418502.1
UniProt: D5Q150
GCF_002303425#BGU60_RS05980
BGU60_RS05980 · HK · Classic
RefSeq: WP_003418502.1
UniProt: D5Q150
GCF_002352505#V439_RS16185
V439_RS16185 · HK · Classic
RefSeq: WP_003418502.1
UniProt: D5Q150
GCF_002412385#V438_RS17525
V438_RS17525 · HK · Classic
RefSeq: WP_003418502.1
UniProt: D5Q150
GCF_002946515#C4E25_RS04355
C4E25_RS04355 · HK · Classic
RefSeq: WP_003418502.1
UniProt: D5Q150
GCF_002946535#C4E42_RS14835
C4E42_RS14835 · HK · Classic
RefSeq: WP_003418502.1
UniProt: D5Q150
GCF_002946555#C4E26_RS04355
C4E26_RS04355 · HK · Classic
RefSeq: WP_003418502.1
UniProt: D5Q150
GCF_003482165#CDIF29020_RS04600
CDIF29020_RS04600 · HK · Classic
RefSeq: WP_003418502.1
UniProt: D5Q150
GCF_003482365#CDIF29747_RS04355
CDIF29747_RS04355 · HK · Classic
RefSeq: WP_003418502.1
UniProt: D5Q150
GCF_003697205#EBB60_RS04795
EBB60_RS04795 · HK · Classic
RefSeq: WP_003418502.1
UniProt: D5Q150
GCF_003697225#EBL90_RS04940
EBL90_RS04940 · HK · Classic
RefSeq: WP_003418502.1
UniProt: D5Q150
GCF_003697245#EBL91_RS04345
EBL91_RS04345 · HK · Classic
RefSeq: WP_003418502.1
UniProt: D5Q150
GCF_004318565#E0Q96_RS01290
E0Q96_RS01290 · HK · Classic
RefSeq: WP_003418502.1
UniProt: D5Q150
GCF_004318785#E0Q93_RS08975
E0Q93_RS08975 · HK · Classic
RefSeq: WP_003418502.1
UniProt: D5Q150
GCF_008579085#F6C11_RS11520
F6C11_RS11520 · HK · Classic
RefSeq: WP_003418502.1
UniProt: D5Q150
GCF_009362915#FTB24_RS14585
FTB24_RS14585 · HK · Classic
RefSeq: WP_003418502.1
UniProt: D5Q150
GCF_012952655#HCN89_RS05050
HCN89_RS05050 · HK · Classic
RefSeq: WP_003418502.1
UniProt: D5Q150
GCF_015351855#ITI91_RS04800
ITI91_RS04800 · HK · Classic
RefSeq: WP_003418502.1
UniProt: D5Q150
GCF_015352255#ITJ05_RS15885
ITJ05_RS15885 · HK · Classic
RefSeq: WP_003418502.1
UniProt: D5Q150
GCF_015732535#CDIF101085_RS04245
CDIF101085_RS04245 · HK · Classic
RefSeq: WP_003418502.1
UniProt: D5Q150
GCF_016766955#JMW53_RS12645
JMW53_RS12645 · HK · Classic
RefSeq: WP_003418502.1
UniProt: D5Q150
GCF_016766975#JMW50_RS01280
JMW50_RS01280 · HK · Classic
RefSeq: WP_003418502.1
UniProt: D5Q150
GCF_016766995#JMW52_RS16380
JMW52_RS16380 · HK · Classic
RefSeq: WP_003418502.1
UniProt: D5Q150
GCF_016767015#JMW49_RS04100
JMW49_RS04100 · HK · Classic
RefSeq: WP_003418502.1
UniProt: D5Q150
GCF_016767035#JMW55_RS01040
JMW55_RS01040 · HK · Classic
RefSeq: WP_003418502.1
UniProt: D5Q150
GCF_016767055#JMW51_RS16320
JMW51_RS16320 · HK · Classic
RefSeq: WP_003418502.1
UniProt: D5Q150
GCF_016767095#JMW48_RS10670
JMW48_RS10670 · HK · Classic
RefSeq: WP_003418502.1
UniProt: D5Q150
GCF_016767115#JMW47_RS07135
JMW47_RS07135 · HK · Classic
RefSeq: WP_003418502.1
UniProt: D5Q150
GCF_016767135#JMW46_RS13860
JMW46_RS13860 · HK · Classic
RefSeq: WP_003418502.1
UniProt: D5Q150
GCF_017592625#J5O10_RS04265
J5O10_RS04265 · HK · Classic
RefSeq: WP_003418502.1
UniProt: D5Q150
GCF_018603395#KK111_RS04525
KK111_RS04525 · HK · Classic
RefSeq: WP_003418502.1
UniProt: D5Q150
GCF_018603455#KK110_RS04520
KK110_RS04520 · HK · Classic
RefSeq: WP_003418502.1
UniProt: D5Q150
GCF_018603475#KK112_RS04510
KK112_RS04510 · HK · Classic
RefSeq: WP_003418502.1
UniProt: D5Q150
GCF_018884725#E1H40_RS04240
E1H40_RS04240 · HK · Classic
RefSeq: WP_003418502.1
UniProt: D5Q150
GCF_019427665#K1N48_RS00580
K1N48_RS00580 · HK · Classic
RefSeq: WP_003418502.1
UniProt: D5Q150
GCF_019427725#K1N54_RS00845
K1N54_RS00845 · HK · Classic
RefSeq: WP_003418502.1
UniProt: D5Q150
GCF_019931025#K8P06_RS14995
K8P06_RS14995 · HK · Classic
RefSeq: WP_003418502.1
UniProt: D5Q150
GCF_020297505#LA365_RS14070
LA365_RS14070 · HK · Classic
RefSeq: WP_003418502.1
UniProt: D5Q150

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_004318565
AssemblyASM431856v1 · Scaffoldhaploid
Genome composition3 643 242 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 92 · HK 46 · RR 46CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key