1 HisKA#1
24-90 aa · 67 aa · 26.7% of protein
Raw token
HisKA:24:1.51e-19:90:67:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
E0R11_RS09875
Histidine kinase, Classic
Clostridioides difficile · GCF_004318545
ClassHKTypeClassicLength251 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_004318545#E0R11_RS09875Stable P2CS identifier used across views.
GenomeGCF_004318545Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length251 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage171 / 251 aa (68.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa251 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
141-244 aa · 104 aa · 41.4% of protein
Raw token
HATPase_c:141:6.66e-31:244:104:109- Raw architecture: HisKA:24:1.51e-19:90:67:64#HATPase_c:141:6.66e-31:244:104:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_004318545::NZ_BIWE01000100.1::G00020
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span1-758Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_004318545::NZ_BIWE01000100.1::G00020Context members
E0R11_RS09875
Partner locus tags
E0R11_RS09875
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_207305228.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagE0R11_RS09875Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_BIWE01000100.1Sequence record reported by the local genomic context database.
Genomic interval1-758 nt758 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1-758 ntGCF_004318545::NZ_BIWE01000100.1::G00020
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_004318545::NZ_BIWE01000100.1::G00020Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_BIWE01000100.1All displayed genes belong to this local TCS context.
Neighborhood span1-758 nt758 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 nt758 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
E0R11_RS09875GCF_004318545#E0R11_RS09875
HKClassicCurrent focus
1-758 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000003215#QAC_RS0213315Use this link to inspect the representative gene detail.
PFAM architectureHAMP + PAS + HisKA + HATPase_c4 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2180212
Simplified PFAM architecture for HKOC_2180212
PFAM domain coverage: 324 / 429 aa (75.5%)
1 aa429 aa
HAMPPASHisKAHATPase_c
- Simplified architecture: HAMP + PAS + HisKA + HATPase_c
- Raw architecture: HAMP[30-74] | PAS[87-193] | HisKA[202-267] | HATPase_c[317-422]
- Domain count: 4
- Matched identifier: HKOC_2180212
- Positioned domains: HAMP 30-74 ; PAS 87-193 ; HisKA 202-267 ; HATPase_c 317-422
Cluster members and taxonomy
Representative gene: GCF_000003215#QAC_RS0213315
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_004318545
AssemblyASM431854v1 · Scaffoldhaploid
Genome composition3 928 133 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 91 · HK 44 · RR 45CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key