Gene detail

E0Q86_RS10570

Histidine kinase, Classic

Clostridioides difficile · GCF_004318425

ClassHKTypeClassicLength367 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_004318425#E0Q86_RS10570Stable P2CS identifier used across views.
GenomeGCF_004318425Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2706982Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_131040540.1 · MIST4 E0Q86_RS10570RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKA_3HATPase_c
Protein length367 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage151 / 367 aa (41.1%)Merged over positioned domains only.
Domain description1 HisKA_3,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa367 aa
HisKA_3: 168-233 aa (66 aa)1HATPase_c: 274-358 aa (85 aa)2
Domain-by-domain annotation2 items
1 HisKA_3#1
168-233 aa · 66 aa · 18.0% of protein
Raw tokenHisKA_3:168:2.14e-20:233:67:68
2 HATPase_c#2
274-358 aa · 85 aa · 23.2% of protein
Raw tokenHATPase_c:274:0.000000000174:358:104:109
  • Raw architecture: HisKA_3:168:2.14e-20:233:67:68#HATPase_c:274:0.000000000174:358:104:109
  • Domain description: 1 HisKA_3,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_004318425::NZ_BIVY01000046.1::G00035
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span29995-31739Genomic interval covered by the local TCS group.
Context group IDGCF_004318425::NZ_BIVY01000046.1::G00035
Context members
E0Q86_RS10565E0Q86_RS10570
Partner locus tags
E0Q86_RS10565E0Q86_RS10570
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_131040540.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagE0Q86_RS10570Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_BIVY01000046.1Sequence record reported by the local genomic context database.
Genomic interval30 635-31 739 nt1 105 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span29 995-31 739 ntGCF_004318425::NZ_BIVY01000046.1::G00035

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_004318425::NZ_BIVY01000046.1::G00035

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_BIVY01000046.1All displayed genes belong to this local TCS context.
Neighborhood span29 995-31 739 nt1 745 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
29 995 nt31 739 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

E0Q86_RS10565GCF_004318425#E0Q86_RS10565
RRNarL

29 995-30 642 nt · Reverse (-)

RefSeq WP_009896181.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2706982Run 6 · HK · 1 sequences
Representative sequenceGCF_004318425#E0Q86_RS10570The current gene is the representative for this cluster.
PFAM architectureHisKA_3 + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2706982

Simplified PFAM architecture for HKOC_2706982

PFAM domain coverage: 150 / 367 aa (40.9%)

1 aa367 aa
HisKA_3: 168-232 aaHisKA_3HATPase_c: 274-358 aaHATPase_c
HisKA_3HATPase_c
  • Simplified architecture: HisKA_3 + HATPase_c
  • Raw architecture: HisKA_3[168-232] | HATPase_c[274-358]
  • Domain count: 2
  • Matched identifier: HKOC_2706982
  • Positioned domains: HisKA_3 168-232 ; HATPase_c 274-358
Cluster members and taxonomy
Visualization

Representative gene: GCF_004318425#E0Q86_RS10570

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_004318425
AssemblyASM431842v1 · Scaffoldhaploid
Genome composition4 076 121 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 106 · HK 51 · RR 55CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key