1 HAMP#1
76-153 aa · 78 aa · 20.1% of protein
Raw token
HAMP:76:0.00000000864:153:78:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
E0Q60_RS18485
Histidine kinase, Classic
Clostridioides difficile · GCF_004317645
ClassHKTypeClassicLength389 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_004317645#E0Q60_RS18485Stable P2CS identifier used across views.
GenomeGCF_004317645Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length389 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage251 / 389 aa (64.5%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa389 aa
Domain-by-domain annotation3 items
2 HisKA#2
165-230 aa · 66 aa · 17.0% of protein
Raw token
HisKA:165:0.00000000126:230:66:643 HATPase_c#3
280-386 aa · 107 aa · 27.5% of protein
Raw token
HATPase_c:280:1.07e-26:386:107:109- Raw architecture: HAMP:76:0.00000000864:153:78:69#HisKA:165:0.00000000126:230:66:64#HATPase_c:280:1.07e-26:386:107:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_004317645::NZ_BIUL01000138.1::G00057
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span90-2225Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_004317645::NZ_BIUL01000138.1::G00057Context members
E0Q60_RS18485E0Q60_RS18490
Partner locus tags
E0Q60_RS18485E0Q60_RS18490
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_330370073.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagE0Q60_RS18485Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_BIUL01000138.1Sequence record reported by the local genomic context database.
Genomic interval90-1 259 nt1 170 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span90-2 225 ntGCF_004317645::NZ_BIUL01000138.1::G00057
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_004317645::NZ_BIUL01000138.1::G00057Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_BIUL01000138.1All displayed genes belong to this local TCS context.
Neighborhood span90-2 225 nt2 136 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
90 nt2 225 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
E0Q60_RS18485GCF_004317645#E0Q60_RS18485
HKClassicCurrent focus
90-1 259 nt · Reverse (-)
E0Q60_RS18490GCF_004317645#E0Q60_RS18490
RROmpR
1 533-2 225 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000449005#QCE_RS02315Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1674773
Simplified PFAM architecture for HKOC_1674773
PFAM domain coverage: 223 / 474 aa (47.0%)
1 aa474 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[188-238] | HisKA[251-315] | HATPase_c[365-471]
- Domain count: 3
- Matched identifier: HKOC_1674773
- Positioned domains: HAMP 188-238 ; HisKA 251-315 ; HATPase_c 365-471
Cluster members and taxonomy
Representative gene: GCF_000449005#QCE_RS02315
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_004317645
AssemblyASM431764v1 · Scaffoldhaploid
Genome composition4 085 179 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 105 · HK 49 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key