Gene detail

E0Q19_RS02845

Histidine kinase, Classic

Clostridioides difficile · GCF_004316745

ClassHKTypeClassicLength274 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_004316745#E0Q19_RS02845Stable P2CS identifier used across views.
GenomeGCF_004316745Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2082201Run 6 · 595 sequences · id 100% · cov 80%
External referencesWP_330556249.1 · MIST4 E0Q19_RS02845RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length274 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage143 / 274 aa (52.2%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa274 aa
HisKA: 67-131 aa (65 aa)1HATPase_c: 177-254 aa (78 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
67-131 aa · 65 aa · 23.7% of protein
Raw tokenHisKA:67:0.00000203:131:65:64
2 HATPase_c#2
177-254 aa · 78 aa · 28.5% of protein
Raw tokenHATPase_c:177:0.00000381:254:90:109
  • Raw architecture: HisKA:67:0.00000203:131:65:64#HATPase_c:177:0.00000381:254:90:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_004316745::NZ_BISS01000008.1::G00010
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span52374-53198Genomic interval covered by the local TCS group.
Context group IDGCF_004316745::NZ_BISS01000008.1::G00010
Context members
E0Q19_RS02845
Partner locus tags
E0Q19_RS02845
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_330556249.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagE0Q19_RS02845Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_BISS01000008.1Sequence record reported by the local genomic context database.
Genomic interval52 374-53 198 nt825 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span52 374-53 198 ntGCF_004316745::NZ_BISS01000008.1::G00010

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_004316745::NZ_BISS01000008.1::G00010

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_BISS01000008.1All displayed genes belong to this local TCS context.
Neighborhood span52 374-53 198 nt825 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
52 374 nt53 198 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2082201Run 6 · HK · 595 sequences
Representative sequenceGCF_000003215#QAC_RS0217010Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2082201

Simplified PFAM architecture for HKOC_2082201

PFAM domain coverage: 143 / 439 aa (32.6%)

1 aa439 aa
HisKA: 233-296 aaHisKAHATPase_c: 342-420 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[233-296] | HATPase_c[342-420]
  • Domain count: 2
  • Matched identifier: HKOC_2082201
  • Positioned domains: HisKA 233-296 ; HATPase_c 342-420
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0217010

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_004316745
AssemblyASM431674v1 · Scaffoldhaploid
Genome composition4 180 507 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 105 · HK 50 · RR 54CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key