1 HisKA#1
87-149 aa · 63 aa · 20.9% of protein
Raw token
HisKA:87:0.00000000181:149:63:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
E0P81_RS05640
Histidine kinase, Classic
Clostridioides difficile · GCF_004316065
ClassHKTypeClassicLength302 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_004316065#E0P81_RS05640Stable P2CS identifier used across views.
GenomeGCF_004316065Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length302 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage168 / 302 aa (55.6%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa302 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
196-300 aa · 105 aa · 34.8% of protein
Raw token
HATPase_c:196:1.12e-23:300:105:109- Raw architecture: HisKA:87:0.00000000181:149:63:64#HATPase_c:196:1.12e-23:300:105:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_004316065::NZ_BIRK01000007.1::G00014
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span65157-66767Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_004316065::NZ_BIRK01000007.1::G00014Context members
E0P81_RS05640E0P81_RS05645
Partner locus tags
E0P81_RS05640E0P81_RS05645
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_000351993.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagE0P81_RS05640Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_BIRK01000007.1Sequence record reported by the local genomic context database.
Genomic interval65 157-66 065 nt909 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span65 157-66 767 ntGCF_004316065::NZ_BIRK01000007.1::G00014
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_004316065::NZ_BIRK01000007.1::G00014Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_BIRK01000007.1All displayed genes belong to this local TCS context.
Neighborhood span65 157-66 767 nt1 611 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
65 157 nt66 767 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
E0P81_RS05640GCF_004316065#E0P81_RS05640
HKClassicCurrent focus
65 157-66 065 nt · Reverse (-)
E0P81_RS05645GCF_004316065#E0P81_RS05645
RROmpR
66 069-66 767 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000289535#SAG0316_RS111550Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2884698
Simplified PFAM architecture for HKOC_2884698
PFAM domain coverage: 168 / 302 aa (55.6%)
1 aa302 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[87-149] | HATPase_c[196-300]
- Domain count: 2
- Matched identifier: HKOC_2884698
- Positioned domains: HisKA 87-149 ; HATPase_c 196-300
Cluster members and taxonomy
Representative gene: GCF_000289535#SAG0316_RS111550
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_004316065
AssemblyASM431606v1 · Scaffoldhaploid
Genome composition4 299 453 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 109 · HK 52 · RR 57CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key