1 HAMP#1
144-207 aa · 64 aa · 14.6% of protein
Raw token
HAMP:144:0.000000381:207:64:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
E0P56_RS06010
Histidine kinase, Classic
Clostridioides difficile · GCF_004315545
ClassHKTypeClassicLength439 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_004315545#E0P56_RS06010Stable P2CS identifier used across views.
GenomeGCF_004315545Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length439 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage207 / 439 aa (47.2%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa439 aa
Domain-by-domain annotation3 items
2 HisKA#2
232-296 aa · 65 aa · 14.8% of protein
Raw token
HisKA:232:0.00000518:296:65:643 HATPase_c#3
342-419 aa · 78 aa · 17.8% of protein
Raw token
HATPase_c:342:0.00000575:419:90:109- Raw architecture: HAMP:144:0.000000381:207:64:69#HisKA:232:0.00000518:296:65:64#HATPase_c:342:0.00000575:419:90:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_004315545::NZ_BIQK01000008.1::G00023
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span74510-76479Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_004315545::NZ_BIQK01000008.1::G00023Context members
E0P56_RS06005E0P56_RS06010
Partner locus tags
E0P56_RS06005E0P56_RS06010
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_131072924.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagE0P56_RS06010Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_BIQK01000008.1Sequence record reported by the local genomic context database.
Genomic interval75 160-76 479 nt1 320 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span74 510-76 479 ntGCF_004315545::NZ_BIQK01000008.1::G00023
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_004315545::NZ_BIQK01000008.1::G00023Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_BIQK01000008.1All displayed genes belong to this local TCS context.
Neighborhood span74 510-76 479 nt1 970 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
74 510 nt76 479 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
E0P56_RS06005GCF_004315545#E0P56_RS06005
RROmpR
74 510-75 163 nt · Forward (+)
E0P56_RS06010GCF_004315545#E0P56_RS06010
HKClassicCurrent focus
75 160-76 479 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_004315545#E0P56_RS06010The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2085065
Simplified PFAM architecture for HKOC_2085065
PFAM domain coverage: 143 / 439 aa (32.6%)
1 aa439 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[233-296] | HATPase_c[342-420]
- Domain count: 2
- Matched identifier: HKOC_2085065
- Positioned domains: HisKA 233-296 ; HATPase_c 342-420
Cluster members and taxonomy
Representative gene: GCF_004315545#E0P56_RS06010
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_004315545
AssemblyASM431554v1 · Scaffoldhaploid
Genome composition4 219 731 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 105 · HK 51 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key