Gene detail

E0P58_RS04460

Histidine kinase, Classic

Clostridioides difficile · GCF_004315425

ClassHKTypeClassicLength302 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_004315425#E0P58_RS04460Stable P2CS identifier used across views.
GenomeGCF_004315425Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2884719Run 6 · 28 sequences · id 100% · cov 80%
External referencesWP_021408245.1 · MIST4 E0P58_RS04460RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length302 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage163 / 302 aa (54.0%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa302 aa
HisKA: 82-144 aa (63 aa)1HATPase_c: 196-295 aa (100 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
82-144 aa · 63 aa · 20.9% of protein
Raw tokenHisKA:82:0.0000000745:144:63:64
2 HATPase_c#2
196-295 aa · 100 aa · 33.1% of protein
Raw tokenHATPase_c:196:2.16e-22:295:100:109
  • Raw architecture: HisKA:82:0.0000000745:144:63:64#HATPase_c:196:2.16e-22:295:100:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_004315425::NZ_BIQE01000008.1::G00011
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span43310-44891Genomic interval covered by the local TCS group.
Context group IDGCF_004315425::NZ_BIQE01000008.1::G00011
Context members
E0P58_RS04455E0P58_RS04460
Partner locus tags
E0P58_RS04455E0P58_RS04460
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021408245.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagE0P58_RS04460Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_BIQE01000008.1Sequence record reported by the local genomic context database.
Genomic interval43 983-44 891 nt909 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span43 310-44 891 ntGCF_004315425::NZ_BIQE01000008.1::G00011

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_004315425::NZ_BIQE01000008.1::G00011

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_BIQE01000008.1All displayed genes belong to this local TCS context.
Neighborhood span43 310-44 891 nt1 582 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
43 310 nt44 891 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

E0P58_RS04455GCF_004315425#E0P58_RS04455
RROmpR

43 310-43 981 nt · Forward (+)

RefSeq WP_021408350.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2884719Run 6 · HK · 28 sequences
Representative sequenceGCF_000450785#QO7_RS09735Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2884719

Simplified PFAM architecture for HKOC_2884719

PFAM domain coverage: 165 / 302 aa (54.6%)

1 aa302 aa
HisKA: 82-144 aaHisKAHATPase_c: 195-296 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[82-144] | HATPase_c[195-296]
  • Domain count: 2
  • Matched identifier: HKOC_2884719
  • Positioned domains: HisKA 82-144 ; HATPase_c 195-296
Cluster members and taxonomy
Visualization

Representative gene: GCF_000450785#QO7_RS09735

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_004315425
AssemblyASM431542v1 · Scaffoldhaploid
Genome composition4 108 474 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 97 · HK 47 · RR 50CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key