Gene detail

E0O89_RS18740

Histidine kinase, Classic

Clostridioides difficile · GCF_004315145

ClassHKTypeClassicLength285 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_004315145#E0O89_RS18740Stable P2CS identifier used across views.
GenomeGCF_004315145Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2453446Run 6 · 200 sequences · id 100% · cov 80%
External referencesWP_131011177.1 · MIST4 E0O89_RS18740RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKA_3HATPase_c
Protein length285 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage151 / 285 aa (53.0%)Merged over positioned domains only.
Domain description1 HisKA_3,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa285 aa
HisKA_3: 86-151 aa (66 aa)1HATPase_c: 192-276 aa (85 aa)2
Domain-by-domain annotation2 items
1 HisKA_3#1
86-151 aa · 66 aa · 23.2% of protein
Raw tokenHisKA_3:86:5.43e-20:151:67:68
2 HATPase_c#2
192-276 aa · 85 aa · 29.8% of protein
Raw tokenHATPase_c:192:0.0000000061:276:104:109
  • Raw architecture: HisKA_3:86:5.43e-20:151:67:68#HATPase_c:192:0.0000000061:276:104:109
  • Domain description: 1 HisKA_3,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_004315145::NZ_BIPQ01000150.1::G00058
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1056-2555Genomic interval covered by the local TCS group.
Context group IDGCF_004315145::NZ_BIPQ01000150.1::G00058
Context members
E0O89_RS18735E0O89_RS18740
Partner locus tags
E0O89_RS18735E0O89_RS18740
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_131011177.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagE0O89_RS18740Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_BIPQ01000150.1Sequence record reported by the local genomic context database.
Genomic interval1 696-2 555 nt860 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span1 056-2 555 ntGCF_004315145::NZ_BIPQ01000150.1::G00058

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_004315145::NZ_BIPQ01000150.1::G00058

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_BIPQ01000150.1All displayed genes belong to this local TCS context.
Neighborhood span1 056-2 555 nt1 500 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 056 nt2 555 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2453446Run 6 · HK · 200 sequences
Representative sequenceGCF_004318545#E0R11_RS17805Use this link to inspect the representative gene detail.
PFAM architectureHisKA_3 + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2453446

Simplified PFAM architecture for HKOC_2453446

PFAM domain coverage: 150 / 399 aa (37.6%)

1 aa399 aa
HisKA_3: 200-264 aaHisKA_3HATPase_c: 306-390 aaHATPase_c
HisKA_3HATPase_c
  • Simplified architecture: HisKA_3 + HATPase_c
  • Raw architecture: HisKA_3[200-264] | HATPase_c[306-390]
  • Domain count: 2
  • Matched identifier: HKOC_2453446
  • Positioned domains: HisKA_3 200-264 ; HATPase_c 306-390
Cluster members and taxonomy
Visualization

Representative gene: GCF_004318545#E0R11_RS17805

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_004315145
AssemblyASM431514v1 · Scaffoldhaploid
Genome composition4 040 282 bp · 28,0% GCClostridioides difficile
Signal transduction countsGenes 100 · HK 48 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key