1 HisKA#1
171-231 aa · 61 aa · 15.7% of protein
Raw token
HisKA:171:0.0000000000428:231:61:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
E0O77_RS14370
Histidine kinase, Classic
Clostridioides difficile · GCF_004314965
ClassHKTypeClassicLength389 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_004314965#E0O77_RS14370Stable P2CS identifier used across views.
GenomeGCF_004314965Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length389 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage161 / 389 aa (41.4%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa389 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
287-386 aa · 100 aa · 25.7% of protein
Raw token
HATPase_c:287:2.51e-25:386:100:109- Raw architecture: HisKA:171:0.0000000000428:231:61:64#HATPase_c:287:2.51e-25:386:100:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_004314965::NZ_BIPH01000083.1::G00040
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span275-1444Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_004314965::NZ_BIPH01000083.1::G00040Context members
E0O77_RS14370
Partner locus tags
E0O77_RS14370
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_235667528.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagE0O77_RS14370Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_BIPH01000083.1Sequence record reported by the local genomic context database.
Genomic interval275-1 444 nt1 170 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span275-1 444 ntGCF_004314965::NZ_BIPH01000083.1::G00040
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_004314965::NZ_BIPH01000083.1::G00040Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_BIPH01000083.1All displayed genes belong to this local TCS context.
Neighborhood span275-1 444 nt1 170 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
275 nt1 444 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
E0O77_RS14370GCF_004314965#E0O77_RS14370
HKClassicCurrent focus
275-1 444 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_004314965#E0O77_RS14370The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2536999
Simplified PFAM architecture for HKOC_2536999
PFAM domain coverage: 166 / 389 aa (42.7%)
1 aa389 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[170-231] | HATPase_c[283-386]
- Domain count: 2
- Matched identifier: HKOC_2536999
- Positioned domains: HisKA 170-231 ; HATPase_c 283-386
Cluster members and taxonomy
Representative gene: GCF_004314965#E0O77_RS14370
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_004314965
AssemblyASM431496v1 · Scaffoldhaploid
Genome composition4 228 062 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 100 · HK 49 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key